The fabrication of a laser based on mesoporous fibers is shown to be possible, demonstrating for the first time that mesostructural systems can be applied as advanced optical materials. The amplification of a guided mode in the fiber and the resulting, gain‐narrowed emission (illustrated on the cover of this issue) are reported. It is stressed that the system used—a composite containing the dye rhodamine 6G—is a relatively simple type of laser material and better results can be expected in the future with different types of lasing guests in mesoporous fibers.