2024
DOI: 10.1101/2024.11.01.621612
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Multi-modal characterization of rodent tooth development

Yuchen Jiang,
Kaitlin A. Katsura,
Nir Z. Badt
et al.

Abstract: Craniofacial tissues undergo hard tissue development through mineralization and changes in physicochemical properties. This study investigates the mechanical and chemical properties of developing enamel, dentin, and bone in the mouse mandible. We employ a multi-modal, multi-scale analysis of the developing incisor and first molar at postnatal day 12 by integrating micro-computed tomography (microCT), nanoindentation (NI), energy dispersive spectroscopy (EDS), and Raman spectroscopy. Our findings demonstrate di… Show more

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