Multi-modal weight control intervention for people with persistent mental disorders.

Abstract

Obesity, a major problem worldwide, is more prevalent among people with schizophrenia. This study examined the effect of behavior intervention, nutritional information and physical exercise on the body mass index (BMI) and weight of people who were hospitalized with persistent DSM-IV schizophrenia and schizoaffective disorders. Fifty nine inpatients with a BMI greater than 25 participated, (28 intervention group; 31 control group). Significant reductions in BMI and weight were observed in the intervention group after 3 months and were maintained 1-year post study [F(1,52) = 6.1, p = .017) and F(1,52) = 3.7, P = .006, respectively]. If provided with adequate information and an appropriate framework, people with persistent schizophrenia can significantly reduce BMI and weight and maintain the loss.

A healthy lifestyle intervention for middle-aged and older schizophrenia patients with diabetes mellitus: A 6-month follow-up analysis

“…(Melamed et al, 2008; Chen et al, 2009; Chwastiak et al, 2009) Comprehensive lifestyle therapies in the general community, however, have shown weight loss of 2 to 10 kilograms (i.e., 4 to 22 pounds) over 10 to 20 weeks, but weight regain over a one-year period. (Hensrud, 2001)…”

Increased Mortality in Schizophrenia Due to Cardiovascular Disease – A Non-Systematic Review of Epidemiology, Possible Causes, and Interventions

“…The combined effect of behavioral intervention, nutritional information, and physical exercise was investigated in a study of people with schizophrenia and body mass index (BMI) exceeding 25. The 3-month intervention program showed significant reduction in weight and BMI, which lasted 12 months (159). Intriguingly, weight reduction was gradual, with increasing weight loss as the program progressed, in contrast to weight reductions patterns in diet programs in healthy individuals, where there is often a larger reduction of weight early on.…”

Weight Loss Intervention for People With Serious Mental Illness: A Randomized Controlled Trial of the RENEW Program

“…Its results are similar to those reported by other studies of weight loss interventions, which found a mean loss of 4.3±5.6 pounds (5). Participants in the RENEW program had maintained their weight loss at six months; other studies indicate that individuals with serious mental illness who have participated in weight loss programs have maintained their weight loss for up to one year (8,9). A subgroup of RENEW participants lost 5% to 10% of body weight, an achievement that is associated with important health benefits such as reduced risk of diabetes and high blood pressure (10).…”