In this paper, a new multi-objective uniform-diversity differential evolution (MUDE) algorithm is proposed and used for Pareto optimum design of mechanisms. The proposed algorithm uses a diversity preserving mechanism called the ε-elimination algorithm to improve the population diversity among the obtained Pareto front. The proposed algorithm is firstly tested on some constrained and unconstrained benchmarks proposed for the special session and competition on multi-objective optimizers held under IEEE CEC 2009. The inverted generational distance (IGD) measure is used to assess the performance of the algorithm. Secondly, the proposed algorithm has been used for multi-objective optimization of two different combinatorial case studies. The first case contains a two-degree of freedom leg mechanism with springs. Three conflicting objective functions that have been considered for Pareto optimization are namely, leg size, vertical actuating force, and the peak crank torque. The second case is a twofinger robot gripper mechanism with two conflicting objectives which are the difference between the maximum and minimum gripping force and the transmission ratio of actuated and experienced gripper forces. Comparisons of obtained Pareto fronts using the method of this work with those obtained in other references show significant improvements.