Multi-objective optimization in biotechnological processes: application to plant cell suspension cultures of Thevetia peruviana

Villegas-Quiceño, Adriana Patricia; Arias-Echeverri, Juan Pablo; Aragón-Mena, Daira; Ochoa-Cáceres, Silvia; Arias-Zabala, Mario

doi:10.17533/udea.redin.n87a05

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…Multiobjective optimization techniques based on metaheuristic algorithms are a suitable tool for the solution of this type of problem [13,14] and are extensively employed in this work.…”

Section: Introductionmentioning

confidence: 99%

Multiobjective topology optimization of planar trusses using stress trajectories and metaheuristic algorithms

Niño-Alvarez

Begambre-Carrillo

2022

Rev.Fac.Ing.Univ.Antioquia

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In civil engineering, structural optimization seeks an efficient use of material resources and the automatization of the design process of a wide range of structures such as frames, bridges, and other systems. This work develops a novel multiobjective topology optimization process to minimize planar trusses' weight and strain energy. In the initial stage, an optimized discrete geometry of the ground structure is generated from a continuum design space with general boundary conditions (loads and supports) using the stress trajectories theory. In the final stage, size optimization is performed using the concept of Envelope Pareto Front (EVP), which is obtained from the best solutions provided by three efficient multiobjective metaheuristic algorithms (NSGA-II, MOPSO and AMOSA). The results obtained on a large-scale truss (200 m span continuous bridge) showed that innovative geometries could be found (new connectivity patterns). The generation of an EVP allows getting a more significant number of non-dominated solutions, exploring a broader region of the Pareto front and the two objective functions, achieving greater convergence and diversity than the algorithms' individual performance. The computation cost of the optimization strategy was satisfactory, which allows its potential implementation in actual large-scale trusses, discovering optimized, innovative solutions for this type of structures.

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“…Multiobjective optimization techniques based on metaheuristic algorithms are a suitable tool for the solution of this type of problem [13,14] and are extensively employed in this work.…”

Section: Introductionmentioning

confidence: 99%

Multiobjective topology optimization of planar trusses using stress trajectories and metaheuristic algorithms

Niño-Alvarez

Begambre-Carrillo

2022

Rev.Fac.Ing.Univ.Antioquia

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“…Many of these biological activities have been attributed to the presence of secondary metabolites such as cardiac glycosides and phenolic compounds (PC); nevertheless, obtaining these metabolites from in vivo plants implies problems such as availability, productivity and reproducibility; therefore, it becomes necessary to have a continuous source of quality biological material for extraction, purification and development of potential therapeutic agents. Consequently, plant cell suspension culture of T. peruviana was established in our laboratory [ 10 ], demonstrating stability in kinetic parameters of cell growth (duplication time, specific growth and substrate consumption rates) over the years [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

FT-NIR spectroscopy and RP-HPLC combined with multivariate analysis reveals differences in plant cell suspension cultures of Thevetia peruviana treated with salicylic acid and methyl jasmonate

Meza

Arias

Cuaspud

et al. 2020

Biotechnology Reports

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Mass propagation of microtubers from suspension cultures of Pinellia ternata cells and quality analysis of the regenerated tubers

Zhang,

Hang,

Yan

et al. 2024

Plant Cell Tiss Organ Cult

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Multi-objective optimization in biotechnological processes: application to plant cell suspension cultures of Thevetia peruviana

Cited by 4 publications

References 13 publications

Multiobjective topology optimization of planar trusses using stress trajectories and metaheuristic algorithms

Multiobjective topology optimization of planar trusses using stress trajectories and metaheuristic algorithms

FT-NIR spectroscopy and RP-HPLC combined with multivariate analysis reveals differences in plant cell suspension cultures of Thevetia peruviana treated with salicylic acid and methyl jasmonate

Mass propagation of microtubers from suspension cultures of Pinellia ternata cells and quality analysis of the regenerated tubers

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