2024
DOI: 10.1101/2024.01.03.574116
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Multi-omic characterization of allele-specific regulatory variation in hybrid pigs

Jianping Quan,
Ming Yang,
Xingwang Wang
et al.

Abstract: Genetic variation in the regulation of gene expression contributes substantially to phenotypic variation. Understanding how variation in DNA sequences and epigentic modifications leads to gene expression variation remains a challenging task. In hybrid animals where cellular environments are homogeneous, differences between the expression of paternal and maternal alleles must be due to cis sequence or epigenic differences. Therefore, hybrid mapping is a powerful approach to efficiently identify and characterize… Show more

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