In Mechanics, material properties are most often regarded as being given, and based on this, many technical solutions are usually conceived and constructed. However, nowadays manufacturing processes have advanced to the point that metamaterials having selected properties can be designed and fabricated. Three-dimensional printing, electrospinning, self-assembly, and many other advanced manufacturing techniques are raising a number of scientific questions which must be addressed if the potential of these new technologies is to be fully realized. In this work, we report on the status of modeling and analysis of metamaterials exhibiting a rich and varied macroscopic response conferred by complex microstructures and particularly focus on strongly interacting inextensible or nearly inextensible fibers. The principal aim is to furnish a framework in which the mechanics of 3D rapid prototyping of microstructured lattices and fabrics can be clearly understood and exploited. Moreover, several-related open questions will be identified and discussed, and some methodological considerations of general interest are provided.