Multi sensor compatible 3D-printed electrochemical cell for voltammetric drug screening

Ferreira, Priscila Alves; Oliveira, Fabiano Mendonça de; Melo, Edmar Isaías de; Carvalho, Adriana Evaristo de; Lucca, Bruno Gabriel; Ferreira, Valdir Souza; Silva, Rodrigo Amorim Bezerra da

doi:10.1016/j.aca.2021.338568

Cited by 33 publications

(12 citation statements)

References 31 publications

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“…2.4.2 3D-printed multi sensor compatible electrochemical cell (3D-MSEC). 17 This cell is composed of three 3D-printed ABS pieces (stick, cover and solution vessel) easily self-assembled by screwing (Fig. 2B).…”

Section: Fabrication and Assembly Of The Stationary Electrochemical C...mentioning

confidence: 99%

“…Thus, the excess insulating polymer must be removed from the surface (enhancing the availability of conductive particles) to improve the electrochemical performance. For this, some surface post-treatment strategies (alone or combined) have been reported in the literature through mechanical polishing, 8,9 solvent immersion, 10–12 electrochemical treatments, 10,12–20 photochemical treatment, 19 carbonization, 21 and reagent-less laser treatment. 22…”

Section: Introductionmentioning

confidence: 99%

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Exploring the coating of 3D-printed insulating substrates with conductive composites: a simple, cheap and versatile strategy to prepare customized high-performance electrochemical sensors

et al. 2022

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Section: Fabrication and Assembly Of The Stationary Electrochemical C...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Exploring the coating of 3D-printed insulating substrates with conductive composites: a simple, cheap and versatile strategy to prepare customized high-performance electrochemical sensors

et al. 2022

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“…The resolution is much higher than the FFF 3D-printed devices, however, longer time of fabrication, the need for post-treatment and curation, and the use of toxic resins are some drawbacks that make SLA less popular than FFF. Nevertheless, one of the first works on the Bismuth film electrodeposition 3D-printed wearable device containing the electrochemical device was fixed at the body using an elastic tape for zinc determination in sweat Dias et al (2019) Images reproduced with permission from American Chemical Society (Snowden et al, 2010;Richter et al, 2019;Sempionatto et al, 2017;Katseli et al, 2021;Dias et al, 2019), Italian Association of Chemical Engineering (Ponce de Leon et al, 2014), Elsevier (Dias et al, 2016;Cardoso et al, 2018;Mendonça et al, 2019;Cardoso et al, 2019;Silva et al, 2020;Escobar et al, 2020;Sibug-Torres et al, 2021;Cardoso et al, 2020c;Ferreira et al, 2021;O'Neil et al, 2019;Baltima et al, 2021); Brazilian Chemical Society (Cardoso et al, 2020a), Royal Society of Chemistry (Elbardisy et al, 2020) and Multidisciplinary Digital Publishing Institute (Vlachou et al, 2020).…”

Section: Examples Of 3d Printer Applications In Electrochemical Devices 3d Printed Electrochemical Cells For Sensing and Other Applicatiomentioning

confidence: 99%

“…A real image of the device constructed using SLA is presented in Table 2 (Cardoso et al, 2020c). Another example was recently reported employing FFF and 3D pen, in which an assembling cell was fabricated by FFF and the 3D pen was used to apply the conductive carbon filament over the created template to serve as counter and reference electrodes (Ferreira et al, 2021). Different planar working electrodes were evaluated for drug screening analysis.…”

Section: Examples Of 3d Printer Applications In Electrochemical Devices 3d Printed Electrochemical Cells For Sensing and Other Applicatiomentioning

confidence: 99%

A 3D Printer Guide for the Development and Application of Electrochemical Cells and Devices

et al. 2021

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3D printing is a type of additive manufacturing (AM), a technology that is on the rise and works by building parts in three dimensions by the deposit of raw material layer upon layer. In this review, we explore the use of 3D printers to prototype electrochemical cells and devices for various applications within chemistry. Recent publications reporting the use of Fused Deposition Modelling (fused deposition modeling®) technique will be mostly covered, besides papers about the application of other different types of 3D printing, highlighting the advances in the technology for promising applications in the near future. Different from the previous reviews in the area that focused on 3D printing for electrochemical applications, this review also aims to disseminate the benefits of using 3D printers for research at different levels as well as to guide researchers who want to start using this technology in their research laboratories. Moreover, we show the different designs already explored by different research groups illustrating the myriad of possibilities enabled by 3D printing.

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“…Fused deposition modeling (FDM) is an innovative 3D printing process in which a sensor is CAD designed and then printed from thermoplastic filaments by a 3D printer. This digital process requires low-cost and desktop-sized printers and it provides ease of operation by non-trained handlers, design flexibility and transferability via e-mail, while it produces eco-friendly and disposable sensors [19][20][21][22][23][24][25][26][27][28][29].…”

Section: Introductionmentioning

confidence: 99%

Fully Integrated 3D-Printed Electronic Device for the On-Field Determination of Antipsychotic Drug Quetiapine

Ragazou

Lougkovois

Katseli

et al. 2021

Sensors

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In this work, we developed a novel all-3D-printed device for the simple determination of quetiapine fumarate (QF) via voltammetric mode. The device was printed through a one-step process by a dual-extruder 3D printer and it features three thermoplastic electrodes (printed from a carbon black-loaded polylactic acid (PLA)) and an electrode holder printed from a non-conductive PLA filament. The integrated 3D-printed device can be printed on-field and it qualifies as a ready-to-use sensor, since it does not require any post-treatment (i.e., modification or activation) before use. The electrochemical parameters, which affect the performance of the sensor in QF determination, were optimized and, under the selected conditions, the quantification of QF was carried out in the concentration range of 5 × 10−7–80 × 10−7 mol × L−1. The limit of detection was 2 × 10−9 mol × L−1, which is lower than that of existing electrochemical QF sensors. The within-device and between-device reproducibility was 4.3% and 6.2% (at 50 × 10−7 mol × L−1 QF level), respectively, demonstrating the satisfactory operational and fabrication reproducibility of the device. Finally, the device was successfully applied for the determination of QF in pharmaceutical tablets and in human urine, justifying its suitability for routine and on-site analysis.

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Multi sensor compatible 3D-printed electrochemical cell for voltammetric drug screening

Cited by 33 publications

References 31 publications

Exploring the coating of 3D-printed insulating substrates with conductive composites: a simple, cheap and versatile strategy to prepare customized high-performance electrochemical sensors

Exploring the coating of 3D-printed insulating substrates with conductive composites: a simple, cheap and versatile strategy to prepare customized high-performance electrochemical sensors

A 3D Printer Guide for the Development and Application of Electrochemical Cells and Devices

Fully Integrated 3D-Printed Electronic Device for the On-Field Determination of Antipsychotic Drug Quetiapine

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