In this introduction to the special series, we examine the emotional and behavioral difficulties of youth of color from a dynamic developmental ecological systems perspective. Building on the concepts of the child-in-context, correlated constraints, systemic oppression, and the malleability of maladaptive patterns, we argue that current research approaches and intervention frameworks (e.g., Multitiered Systems of Support, Positive Behavioral Interventions and Support) are centered on the experiences and circumstances of youth from majority backgrounds. This creates a context in which the emotional and behavioral difficulties of youth of color reflect a continuum of services casualty in which routine daily supports, interventions, and services are not aligned with their developmental needs and their corresponding pathways to success. There is a need to establish a targeted-universalism approach in which interventions and supports are centered on the daily functioning and adaptation of underrepresented groups. We discuss how a tiered system of adaptive supports may be designed and implemented to address this need.