This paper proposes a comprehensive solution to reduce peak-to-average power ratio (PAPR), cancel out-of-band emission (OOBE), and alleviate the impact of phase noise for precoded orthogonal frequency-division multiplexing (OFDM) systems. Making use of the cancellation and pilot symbols and subcarriers in both data and frequency domains, this solution integrates a number of novel schemes to overcome OFDM's inherent drawbacks and mitigate practical impairments for high speed wireless communications. These schemes include a layered precoding structure, a low complexity OOBE cancellation using both data domain cancellation symbols and frequency domain cancellation subcarriers, and an effective phase noise compensation using data domain pilot symbols. The improved overall system performance of the proposed solution is verified by simulation results.Index Terms-High speed wireless transmission, OFDM, peakto-average power ratio, out-of-band emission, and phase noise.