Multicentre experience with extralevator abdominoperineal excision for low rectal cancer

West, Nicholas P.; Anderin, Claes; Smith, Katherine J.; Holm, Torbjörn; Quirke, Philip

doi:10.1002/bjs.6916

Cited by 369 publications

(396 citation statements)

References 33 publications

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“…Sie führt zu qualitativ höherwertigen Präparaten [708,709]. Höhere Komplikationsraten scheinen mit Erhöhung der Radikalität nicht verbunden zu sein [710].…”

Section: Vorgehen Bei Karzinomen Des Mittleren Colon Transversumunclassified

“…De Novo: [709,754,755] Konsens Hintergrund Bei der Rektum-Exstirpation ist klassisch die Rate an Präpara-ten mit unzureichenden lateralen Sicherheitsabständen erhöht [754]. Die onkologischen Ergebnisse sind gegenüber Sphinktererhaltenden Eingriffen bei vergleichbaren Tumorstadien schlechter [755].…”

Section: Level Of Evidence 3bunclassified

“…Die onkologischen Ergebnisse sind gegenüber Sphinktererhaltenden Eingriffen bei vergleichbaren Tumorstadien schlechter [755]. Die extralevatorische "zylindrische" Resektion führt zu besseren Sicherheitsabständen und muss auch ohne Beweis durch randomisierte Studien als das überlegene Verfahren angesehen werden [709].…”

Section: Level Of Evidence 3bunclassified

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S3-Leitlinie – Kolorektales Karzinom

Schmiegel

Buchberger

Follmann³

et al. 2017

Z Gastroenterol

151

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“…Sie führt zu qualitativ höherwertigen Präparaten [708,709]. Höhere Komplikationsraten scheinen mit Erhöhung der Radikalität nicht verbunden zu sein [710].…”

Section: Vorgehen Bei Karzinomen Des Mittleren Colon Transversumunclassified

Section: Level Of Evidence 3bunclassified

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S3-Leitlinie – Kolorektales Karzinom

Schmiegel

Buchberger

Follmann³

et al. 2017

Z Gastroenterol

151

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“…It is difficult to ascertain if APR or absence of IC was responsible for high CRM positivity. A case can be made for extra levator APR which in multicenter observational study has shown to be superior to standard APR in terms of positive CRM (West et al, 2010). Although IC demonstrated favorable role in terms of sphincter preservation, CRM negativity and overall survival; prospective studies with larger sample size and longer follow up are needed to validate the results of current study.…”

Section: Discussionmentioning

confidence: 72%

Can Induction Chemotherapy before Concurrent Chemoradiation Impact Circumferential Resection Margin Positivity and Survival in Low Rectal Cancers?

Bhatti¹,

Waheed²,

Hafeez³

et al. 2015

Asian Pacific Journal of Cancer Prevention

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“…During the first approach the perineal excision is performed, the specimen resected and retrieved (waist model), presacral space drained and wound approximated in layers, whereas in the extralevator excision the resected specimen has cylindrical shape. It is currently suggested that R0 resections and circumferential resection margins (CRM) involvement are improved in the extralevator resection [120].…”

Section: 7% [Consensus]; Gor A: 857% [Consensus])mentioning

confidence: 99%

Laparoscopic extraperitoneal rectal cancer surgery: the clinical practice guidelines of the European Association for Endoscopic Surgery (EAES)

et al. 2011

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Background The laparoscopic approach is increasingly applied in colorectal surgery. Although laparoscopic surgery in colon cancer has been proved to be safe and feasible with equivalent long-term oncological outcome compared to open surgery, safety and long-term oncological outcome of laparoscopic surgery for rectal cancer remain controversial. Laparoscopic rectal cancer surgery might be efficacious, but indications and limitations are not clearly defined. Therefore, the European Association for Endoscopic Surgery (EAES) has developed this clinical practice guideline. Methods An international expert panel was invited to appraise the current literature and to develop evidence-based recommendations. The expert panel constituted for a consensus development conference in May 2010. Thereafter, the recommendations were presented at the annual congress of the EAES in Geneva in June 2010 in a plenary session. A second consensus process (Delphi process) of the recommendations with the explanatory text was necessary due to the changes after the consensus conference. Results Laparoscopic surgery for extraperitoneal (midand low-) rectal cancer is feasible and widely accepted. The laparoscopic approach must offer the same quality of surgical specimen as in open surgery. Short-term outcomes such as bowel function, surgical-site infections, pain and hospital stay are slightly improved with the laparoscopic approach. Laparoscopic resection of rectal cancer is not

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Multicentre experience with extralevator abdominoperineal excision for low rectal cancer

Abstract: Extralevator APE is associated with less CRM involvement and IOP than standard surgery.

Cited by 369 publications

References 33 publications

S3-Leitlinie – Kolorektales Karzinom

S3-Leitlinie – Kolorektales Karzinom

Can Induction Chemotherapy before Concurrent Chemoradiation Impact Circumferential Resection Margin Positivity and Survival in Low Rectal Cancers?

Laparoscopic extraperitoneal rectal cancer surgery: the clinical practice guidelines of the European Association for Endoscopic Surgery (EAES)

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