2010
DOI: 10.1021/ac9025994
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Multichannel Capillary Electrophoresis Microdevice and Instrumentation for in Situ Planetary Analysis of Organic Molecules and Biomarkers

Abstract: The Multichannel Mars Organic Analyzer (McMOA), a portable instrument for the sensitive microchip capillary electrophoresis (CE) analysis of organic compounds such as amino acid biomarkers and polycyclic aromatic hydrocarbons (PAHs), is developed. The instrument uses a four-layer microchip, containing eight CE analysis systems integrated with a microfluidic network for autonomous fluidic processing. The McMOA has improved optical components that integrate 405 nm laser excitation with a linear-scanning optical … Show more

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Cited by 62 publications
(54 citation statements)
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References 38 publications
(72 reference statements)
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“…If a target compound is not itself fluorescent, it can be labeled with the addition of a specific compound that does fluoresce efficiently—a fluorophore tag. The autofluorescence of organic molecules and whole microorganisms, as well as applicable fluorophore dyes, is being investigated for use in biosignature detection instruments (Nadeau et al , 2008; Weinstein et al , 2008; Storrie-Lombardi et al , 2009; Benhabib et al , 2010; Dartnell et al , 2010). …”
Section: Chapter 7 What Are the Signs Of Life (Biosignatures) That Wmentioning
confidence: 99%
“…If a target compound is not itself fluorescent, it can be labeled with the addition of a specific compound that does fluoresce efficiently—a fluorophore tag. The autofluorescence of organic molecules and whole microorganisms, as well as applicable fluorophore dyes, is being investigated for use in biosignature detection instruments (Nadeau et al , 2008; Weinstein et al , 2008; Storrie-Lombardi et al , 2009; Benhabib et al , 2010; Dartnell et al , 2010). …”
Section: Chapter 7 What Are the Signs Of Life (Biosignatures) That Wmentioning
confidence: 99%
“…The authors claimed 95% accuracy for multiplexed measurements (172). Mathies and co-workers have developed a prototype multichannel Mars organic analyzer capable of performing CE assays of organic sugars, aldehydes, and acids (173). A continuous microanalyzer has been developed by integrating microfluidics and electronics for two different analytes K 4 Fe(CN) 6 and free chlorine (174).…”
Section: Technologymentioning
confidence: 99%
“…An in-situ CE system which used a four-layer chip and contained eight CE systems has been designed by Benhabib et al [100]. The system included a completely autonomous fluidic control system and it was demonstrated by analysing a variety of organic compounds.…”
Section: In-situ Ce Systemsmentioning
confidence: 99%