Multichannel Electrogastrography (EGG) in Normal Subjects: A Multicenter Study

Abstract

The aim of this study was to record gastric myoelectric activity using multichannel electrogastrography (EGG) and to determine if there are differences due to age, gender, body mass, and study location. In 61 normal subjects from four centers, fasting multichannel EGG was recorded for 1 h, followed by two 1-h postprandial recordings after a test meal. Variables assessed included dominant frequency (DF) and its power, percentage time in 2- to 4-cpm frequency, and percentage slow-wave coupling (%SWC). There were no significant differences in EGG parameters with respect to gender or age. Subjects with a BMI > 25 had a decrease in the absolute DF power but a similar increase in the postprandial DF power. Subjects with a BMI > 25 had a postprandial decrease in the %SWC compared to those with a BMI < 25. There was a decrease in postprandial %SWC in European/Asian centers compared to American centers. In conclusion, multichannel EGG provides assessment of electrical slow-wave coupling in addition to determining dominant frequency, power, and percentage normal rhythm. This multicenter study of normal subjects shows similar multichannel EGG values among different genders and ages. Body mass and ethnicity may impact on some of the EGG values.

The influence of opioids on gastric function: experimental and clinical studies

“…Electrogastrography (IV) Compared to historical controls (157), there were no differences in the baseline EGG variables.…”

“…An overall spectrum analysis was performed on each of the two main 30-minute segments (before and after fentanyl, respectively) of the selected channel using the entire time-domain EGG signal (157). Sequential sets of measurement data for 256s with an overlap of 196s were analyzed using fast Fourier transforms and a…”

“…Data from the baseline EGG were compared to data from a previous multicenter study in normal subjects (157) to test if the group in study IV was similar to a normal population.…”

Gastric myoelectrical activity in children and youth with gastroesophageal reflux disease

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Comparison of multichannel electrogastrograms obtained with the use of three different electrode types

“…Electrogastrography evolves, however, still further. Introduction and validation of the methodology of recording and analysing a multichannel electrogastrogram (Chen et al, 1999;Liang, 2005;Lin and Chen, 2001;McNearney et al, 2002;Wang et al, 2003) was followed soon by a proposal of normal ranges of electrogastrographic parameters designed as quantitative descriptors of the spread of slow waves throughout the stomach, such as: the (A)PSWC = (average) percentage of slow-wave coupling, the MDFD = maximum dominant frequency difference, the SDPD = spatial dominant power difference (Medtronic A/S, 2002;Simonian et al, 2004aSimonian et al, , 2004b. The multichannel variety of electrogastrography remains, however, a novelty and huge research work still has to be done until its potential advantages over the 'classical' single channel approach will have ultimately and unequivocally been proven.…”