The modern view of Earth's lowermost mantle considers a D″ region of enhanced (seismologically inferred) heterogeneity bounded by the core-mantle boundary and an interface some 150-300 km above it, with the latter often attributed to the postperovskite phase transition (in MgSiO 3 ). Seismic exploration of Earth's deep interior suggests, however, that this view needs modification. Socalled ScS and SKKS waves, which probe the lowermost mantle from above and below, respectively, reveal multiple reflectors beneath Central America and East Asia, two areas known for subduction of oceanic plates deep into Earth's mantle. This observation is inconsistent with expectations from a thermal response of a single isochemical postperovskite transition, but some of the newly observed structures can be explained with postperovskite transitions in differentiated slab materials. Our results imply that the lowermost mantle is more complex than hitherto thought and that interfaces and compositional heterogeneity occur beyond the D″ region sensu stricto.seismic imaging | mineral physics | mantle convection T he lowermost mantle, extending several hundred kilometers above the ∼2,900-km-deep core-mantle boundary (CMB), is of considerable interest because it includes the boundary layer of thermochemical mantle convection across which heat is conducted from the core into the mantle. Almost three decades after the detection of an interface some 150-300 km above the CMB (1), the base of the mantle is still a challenging target for crossdisciplinary research. Both the seismic discontinuity that marks the top of the so-called D″ region (1) and the heterogeneity below it (2, 3) have been attributed to a perovskite (Pv) to postperovskite (pPv) transition in the dominant mantle silicate (4-8), and this association has inspired estimation of temperatures above and heat flux across the CMB (9, 10). The D″ interface remains enigmatic, however, and recent high pressure-temperature experiments suggest that seismic observations concerning its depth and thickness are inconsistent with those expected for a pPv transition unless the chemical composition of the regions where they occur differs significantly from standard bulk composition models such as pyrolite (11-13). The transition thickness could be reconciled with nonlinearity in the phase fraction profile (11) or lattice preferred orientation in pPv (14), but the depth is a concern because the pPv transition pressure in pyrolite may be too high for it to occur in the lower mantle (13). Candidate compositions for a seismically detectable pPv transition at mantle pressures include midoceanic ridge basalt (MORB) and harzburgite components of subducted and differentiated oceanic lithosphere. Furthermore, silica may transform from modified stishovite to seifertite in Si-rich parts of the lowermost mantle (15). Inspired by these results, we search for multiple interfaces in and above the conventional D″ region, using seismic waves that sample the lowermost mantle beneath geographic regions where seismic...