The Lie sphere geometry is a natural extension of the Möbius geometry, where the latter is very important in string theory and the AdS/CFT correspondence. The extension to Lie sphere geometry is applied in the following to a sequence of Möbius geometries, which has been investigated recently in a bicomplex matrix representation. When higher dimensional space-time geometries are invoked by inverse projections starting from an originating point geometry, the Lie sphere scheme provides a more natural structure of the involved Clifford algebras compared to the previous representation. The spin structures resulting from the generated Clifford algebras can potentially be used for the geometrization of internal particle symmetries. A simple model, which includes the electromagnetic spin, the weak isospin, and the hadronic isospin, is suggested for further verification.