In Italy, it has always been difficult to collect reliable data on real estate given the opacity of the information available. Keeping into consideration the actual availability of data and information, the possibility to have a structure for permanently monitoring and analysing the real estate market is fundamental. Focusing on developing and disseminating knowledge related to practices in this context, in this paper the Turin's (Northern Italy) experience is presented, through the Real Estate Market Observatory (TREMO): This structure is based on a data-warehouse, implemented over time, with databases that lead to historic price observations of the residential market. The data warehouse is the basis for investigating methodologies and analyses, assuming the spatial requisites of the data and its georeferencing as the main discriminant in choosing among descriptive statistics, multi-varied or spatial analysis methods. In twenty years, several studies have been developed, allowing us not only to explore the applicability of models and operative modalities, but also to obtain results with a high potential impact under a social viewpoint. In this paper, the methodologies developed for implementing the monitoring structure are presented, specifically the "quality process" and computerized analysis procedures, followed by some representative research experiences with reference to aims, models and results.