Multidetector CT enterography of focal small bowel lesions: a radiological–pathological correlation

Sokhandon, Farnoosh; Al‐Katib, Sayf; Bahoura, Lawrence; Copelan, Alexander; George, Daniel J.; Scola, Dominic

doi:10.1007/s00261-016-1015-1

Cited by 26 publications

(41 citation statements)

References 61 publications

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“…Un compromiso generalizado o multifocal intestinal, la ausencia de obstrucción a pesar de gran volumen tumoral y la ausencia de hipervascularización, son señales que apuntan hacia un linfoma. En el colon, particularmente en el ciego, y el recto, las lesiones pueden ser masa polipoide, infiltración circunferencial, masa ulcerada, haustras engrosadas o nódulos mucosos 13,14 .…”

Section: Discussionunclassified

Complicaciones quirúrgicas del linfoma con compromiso gastrointestinal

Molina-Valencia

Delgado-López

2021

Rev Colomb Cir

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Introducción. El linfoma puede afectar el tracto gastrointestinal de manera primaria o secundaria, y representa hasta el 2 % de todas las neoplasias malignas del intestino delgado y colon. El tracto gastrointestinal es la ubicación extraganglionar primaria más común en el linfoma no Hodgkin. Métodos. Se realizó una búsqueda de la literatura en las principales bases de datos académicas, con revisión de textos publicados sobre el tema en los últimos 5 años. Discusión. La presentación clínica del linfoma con compromiso gastrointestinal es inespecífica y, hasta en la mitad de los pacientes, se puede presentar de manera inicial con complicaciones que requieran manejo quirúrgico. Entre las principales se encuentran la perforación intestinal, el sangrado digestivo y la obstrucción intestinal.

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Section: Discussionunclassified

Complicaciones quirúrgicas del linfoma con compromiso gastrointestinal

Molina-Valencia

Delgado-López

2021

Rev Colomb Cir

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“…Circumferential irregular wall thickening of the duodenum is a typical imaging appearance of duodenal or ampullary adenocarcinoma (Fig 9). Although uncommon, jejunal polyps are identified as enhancing sessile nodules at CT enterography or MR enterography (37). At doublecontrast barium enema study, multiple polyps measuring from pinhead size up to 1.5 cm and giving a serrated contour to the colonic wall are commonly seen (38).…”

Section: Familial Adenomatous Polyposismentioning

confidence: 99%

Hereditary Gastrointestinal Cancer Syndromes: Role of Imaging in Screening, Diagnosis, and Management

Katabathina¹,

Menias

Khanna³

et al. 2019

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Hereditary gastrointestinal (GI) cancer syndromes due to specific germline mutations are characterized by an increased risk of GI tract malignancies, extra-GI tract cancers, and benign abnormalities. These syndromes include Lynch syndrome, familial adenomatous polyposis, juvenile polyposis syndrome, Peutz-Jeghers syndrome, Cowden syndrome, hereditary diffuse gastric cancer, and hereditary pancreatic cancer. Timely identification of the responsible genes will help predict future cancer risks in these patients and their family members. Early detection of cancers is possible with appropriate screening methods; risk-reducing measures will help in cancer prevention. Select malignancies and benign conditions associated with these syndromes have distinctive imaging features that can aid in classifying the syndromes. Imaging also plays a pivotal role in screening and surveillance of patients as well as their at-risk relatives and is invaluable for follow-up of treated malignancies. The American College of Gastroenterology has established specific guidelines for diagnosis and management of hereditary GI cancer syndromes. Knowledge of the imaging features of various pathologic conditions and screening strategies will guide appropriate management of patients and at-risk family members. ©

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“…Circumferential extension may result in bowel obstruction. Haziness of the surrounding fat may suggest transmural invasion (63).…”

Section: Screening and Imagingmentioning

confidence: 99%

Lynch Syndrome: Genomics Update and Imaging Review

et al. 2018

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Lynch syndrome is the most common hereditary cancer syndrome, the most common cause of heritable colorectal cancer, and the only known heritable cause of endometrial cancer. Other cancers associated with Lynch syndrome include cancers of the ovary, stomach, urothelial tract, and small bowel, and less frequently, cancers of the brain, biliary tract, pancreas, and prostate. The oncogenic tendency of Lynch syndrome stems from a set of genomic alterations of mismatch repair proteins. Defunct mismatch repair proteins cause unusually high instability of regions of the genome called microsatellites. Over time, the accumulation of mutations in microsatellites and elsewhere in the genome can affect the production of important cellular proteins, spurring tumorigenesis. Universal testing of colorectal tumors for microsatellite instability (MSI) is now recommended to (a) prevent cases of Lynch syndrome being missed owing to the use of clinical criteria alone, (b) reduce morbidity and mortality among the relatives of affected individuals, and (c) guide management decisions. Organ-specific cancer risks and associated screening paradigms vary according to the sex of the affected individual and the type of germline DNA alteration causing the MSI. Furthermore, Lynch syndrome-associated cancers have different pathologic, radiologic, and clinical features compared with their sporadic counterparts. Most notably, Lynch syndrome-associated tumors tend to be more indolent than non-Lynch syndrome-associated neoplasms and thus may respond differently to traditional chemotherapy regimens. The high MSI in cases of colorectal cancer reflects a difference in the biologic features of the tumor, possibly with a unique susceptibility to immunotherapy. RSNA, 2018.

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Multidetector CT enterography of focal small bowel lesions: a radiological–pathological correlation

Cited by 26 publications

References 61 publications

Complicaciones quirúrgicas del linfoma con compromiso gastrointestinal

Complicaciones quirúrgicas del linfoma con compromiso gastrointestinal

Hereditary Gastrointestinal Cancer Syndromes: Role of Imaging in Screening, Diagnosis, and Management

Lynch Syndrome: Genomics Update and Imaging Review

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