Multidisciplinary approach to maximize angiogenesis and wound healing using piezoelectric surgery, concentrated growth factors and photobiomodulation for dental implant placement surgery involving lateral wall sinus lift: two case reports.

Abstract

Background : The combined application of surgical and therapeutic modalities to improve the rate and or degree of healing and tissue regeneration is gaining in popularity. Aim : This study describes two case reports using piezoelectric surgery (PES), concentrated growth factors (CGF) and photobiomodulation (PBM) as a means of enhancing angiogenesis and tissue regeneration following dental implant sinus lift procedures. Materials and Methods : Sinus lateral windows were created using PES and the sinus membrane raised to make a new partition. Dental implants were inserted concurrently and packed with autologous fibrin rich CGF. Wound sites underwent PBM treatment using a multiwave locked system laser. The efficacy of the multidisciplinary approach was assessed by radiographic and clinical evaluation one, three, six, ten, and twelve-months post-surgery. Results : Postoperative revival was ordinary with no noteworthy postoperative complications. Wound closure and angiogenesis occurred shortly after day one. New bone formation in all augmented maxillary sinuses was detected alongside the implants on plain radiographs and on conebeam computed tomograms. The patients were highly satisfied (>80%) with the treatment regime and the success rate of the implants was 100% after a usual 10 months loading period. Conclusion : PBM, PES, and CGF promoted angiogenesis and wound healing following lateral wall sinus lift by increasing wound approximation and decreasing bleeding and swelling. Patients recorded less postoperative pain, speech impairment, analgesic use and trismus.

Comparison of calcium sulfate and tricalcium phosphate in bone grafting after sinus lifting for dental implantation: A randomized controlled trial

“…23 After maxillary sinus grafting, the bony window was covered with an absorbable collagen membrane on the side grafted with the TCP/APRF compound, which helps to prevent the surrounding connective tissue cells from entering the bone graft material and increases vital bone formation. 24 No membrane was used for the CS/APRF compound, and the window was covered only with the CS graft material. The material can be used as a membrane due to its physical properties, 15 which reduces the finan cial cost and the surgical procedure time.…”

Growth Characteristics and Efficacy of Umbilical Cord Lining Mesenchymal Stem Cells in Burn Wound Treatment

“…Additionally, cultured conjunctival transplantation has emerged as a viable approach for reconstructing the ocular surface and treating various eye diseases [11,12]. In cases of bilateral limbal stem cell loss, bioengineered oral mucosal epithelial cell transplantation has been proposed as an alternative solution [13][14][15]. Unfortunately, transplanted stem cells often experience reduced proliferative capacity over time, leading to graft failure and the need for repeated transplantation [9].…”

Evaluation of the use of heterologous fibrin biopolymer and hydroxyapatite/tricalcium phosphate synthetic ceramic, associated or not with photobiomodulation therapy, in the repair of bone defects

“…However, the study by Doan et al, (2020) the clinical applicability of the combination of autologous concentrated growth factors (CGF) and photobiomodulation (PBM) was made. Lateral sinus windows were created using piezoelectric surgery (PES) and the dental implants were concurrently fixated and wrapped with autologous fibrin (AF) rich CGF.…”