Multidisciplinary collaboration for the successful treatment of a giant hepatic solitary fibrous tumor protruding into the thorax: A case report

Abstract

Solitary fibrous tumors (SFTs) are composed of spindle cells and collagen fibers, and these form rare mesenchymal tumors. SFTs are most frequently observed in intrathoracic sites; however, they may also occur in extrathoracic sites, such as the liver. Unlike the hepatic SFTs (HSFTs) reported in the literature, the SFT detailed in the present case report was a large tumor that originated from the liver, with a dumbbell-shaped growth through the diaphragm into the right thoracic cavity. This posed substantial challenges in both diagnosis and treatment. Thus, the present report outlines the findings of a multidisciplinary team meeting that was used to discuss and develop an optimal and personalized treatment strategy for the patient. Transhepatic arterial embolization was performed to block the major arterial blood supply to the tumor in order to reduce its size. Subsequently, the tumor was fully resected, following the collaboration of the experienced hepatobiliary and thoracic surgeons. Following surgery, the abdominal distension experienced by the patient ceased, and no tumor recurrence was detected at the 1-year follow-up. In conclusion, due to limited previous reports of HSFT treatment using multidisciplinary collaboration, the present study outlined the treatment used for this specific tumor type, and the corresponding literature was reviewed.

A giant solitary fibrous tumor of the abdominal pelvic cavity: A case report and literature review

“…[23] Study demonstrated that the 5-year survival rate of patients who underwent curative resection ranging from 59% to 100%, and 10-year survival ranging from 40% to 89% have been observed when choosing complete curative resection. [2,[24][25][26] Therefore, curative resection could significantly improve the prognosis of giant abdominal-pelvic SFT and the prognosis of SFTs is often associated with resectability. Most of abdominal-pelvic SFT have a good prognosis without postoperative recurrence or metastasis, the recurrence of tumor was statistically related to capsule integrity for giant SFT.…”

“…Thus, patients require long-term follow-up, considering the relatively good prognosis of SFT, adjuvant chemoradiation therapy after surgery is not recommended. [2] Chemoradiation therapy is utilized in cases of non-resectable tumors. [27] Increasing number of studies suggest that radiation therapy may reduce local recurrence, but no increase overall survival time.…”

“…Solitary fibrous tumor (SFT) is a rare mesenchymal tumor originated from CD34 positive dendritic mesenchymal cells that may occur virtually anywhere throughout the body, [1,2] within the abdominal pelvic cavity are particularly rare, especially giant tumors (up to 20 cm in diameter). [3][4][5] The imaging features of SFT are many and varied, and preoperative diagnosis is difficult.…”