Multidisciplinary consensus document on the management of massive haemorrhage (HEMOMAS document)

Llau, J.V.; Acosta, F; Escolar, Ginés; Fernández-Mondéjar, E.; Guasch, E.; Marco, Pascual; Paniagua, Pilar; Páramo, José A.; Quintana, Manuel; Torrabadella, P.

doi:10.1016/j.medine.2015.10.001

Cited by 20 publications

(32 citation statements)

References 209 publications

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“…[339][340][341][342][343][344] Because thromboembolic events after the administration of PCC have been related to high doses, it is advisable that the repeated administration of PCC should be guided by the effect on the INR: if INR is less than 1.5 we suggest not administering another dose of PCC, although clinical parameters should also be assessed. 345 Activated PCCs are not indicated for the reversal of VKAinduced anticoagulation even in emergency bleeding situations. Their use should be restricted to patients with haemophilia A and B with inhibitors to coagulation factors VIII or IX for control and prevention of bleeding episodes, perioperative management or routine prophylaxis to prevent or reduce the frequency of bleeding episodes.…”

Section: Prothrombin Complex Concentrate and Nonvitamin K-dependent Omentioning

confidence: 99%

Management of severe perioperative bleeding

Kozek‐Langenecker

Ahmed

Afshari

et al. 2017

European Journal of Anaesthesiology

694

316

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: The management of perioperative bleeding involves multiple assessments and strategies to ensure appropriate patient care. Initially, it is important to identify those patients with an increased risk of perioperative bleeding. Next, strategies should be employed to correct preoperative anaemia and to stabilise macrocirculation and microcirculation to optimise the patient's tolerance to bleeding. Finally, targeted interventions should be used to reduce intraoperative and postoperative bleeding, and so prevent subsequent morbidity and mortality. The objective of these updated guidelines is to provide healthcare professionals with an overview of the most recent evidence to help ensure improved clinical management of patients. For this update, electronic databases were searched without language restrictions from 2011 or 2012 (depending on the search) until 2015. These searches produced 18 334 articles. All articles were assessed and the existing 2013 guidelines were revised to take account of new evidence. This update includes revisions to existing recommendations with respect to the wording, or changes in the grade of recommendation, and also the addition of new recommendations. The final draft guideline was posted on the European Society of Anaesthesiology website for four weeks for review. All comments were collated and the guidelines were amended as appropriate. This publication reflects the output of this work.

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Section: Prothrombin Complex Concentrate and Nonvitamin K-dependent Omentioning

confidence: 99%

Management of severe perioperative bleeding

Kozek‐Langenecker

Ahmed

Afshari

et al. 2017

European Journal of Anaesthesiology

694

316

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“…Firm evidence supports the recommendation to correct these factors in massive hemorrhage. 5 As regards communication and teamwork, close monitoring and precise documentation of the observations and times is required throughout the duration of the MOH episode. It is important to inform other team members of well-founded suspicions on an early basis.…”

Section: Medical Treatmentmentioning

confidence: 99%

“…5 The use of TXA has been shown to reduce the amount of bleeding and the need for transfusion in nonobstetric massive hemorrhage. Its administration in MOH has not been fully established to date, though it is increasingly used in daily practice, in view of the favorable results obtained in major surgery and in trauma.…”

Section: Plateletsmentioning

confidence: 99%

Massive obstetric hemorrhage: Current approach to management

Guasch

Gilsanz

2016

Medicina Intensiva (English Edition)

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“…In addition, when a postpartum atony occurs there may be a large amount of blood retained in the uterus, whether the delivery was by caesarean section, or if it was a eutocic delivery. 18,19 DIAGNOSTIC CRITERIA According to the Mexican Clinical Practice Guidelines, the diagnostic criteria to obstetric hemorrhage are: -Lost more than 25% of the volume. (50% of the volume in 3 hours).…”

Section: Rcog* United Kingdom 2009 17mentioning

confidence: 99%

“…General anesthesia is preferred in hemodynamically unstable patients with coagulopathy. 18,24 Hysterectomy continues to be the option of bleeding control to save the life of the patient. It is done to save life and before triggering a coagulopathy.…”

Section: Radical Surgerymentioning

confidence: 99%

Obstetric Hemorrhage, its role in maternal morbidity and mortality and the importance of its diagnosis, prevention and timely management

Espinoza¹

2020

Mex J Med Res

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Background: In recent years, different international and national campaigns have been implemented to combat obstetric haemorrhage. Maternal mortality (MM) is one of the main concerns of public health and represents a good indicator to measure the quality of care, an indicator that also allows to establish the socioeconomic differences between countries. There are still many activities to be carried out and achieve the objective set by the World Health Organization (WHO) and the Latin American Federation of Societies in Obstetrics and Gynaecology (FLASOG) "Zero deaths due to haemorrhage". Objective: Based on the scientific evidence available, deepen the knowledge of the role of obstetric haemorrhage as the main avoidable cause of maternal morbidity and mortality. Methodology: retrospective study through the search of original articles and systematic reviews in: Elsevier, Lancet, Intramed, PubMed, EMBASE, ScienceDirect and Cochrane Library. The following keywords were used for all sites: "Obstetric haemorrhage", "Maternal mortality and obstetric haemorrhage", "Maternal morbidity and obstetric haemorrhage", "Postpartum, late, secondary haemorrhage". The items with the highest level of evidence were selected. Conclusions: Obstetric haemorrhage is still a potential cause of maternal and fetal morbidity and mortality. Its appearance at any time of pregnancy is a cause for concern and alarm. Despite advances in obstetric and anesthetic care, its treatment remains a challenge for the surgical team, anesthesiologist, gynaecologist and Pediatrician.

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Multidisciplinary consensus document on the management of massive haemorrhage (HEMOMAS document)

Cited by 20 publications

References 209 publications

Management of severe perioperative bleeding

Management of severe perioperative bleeding

Massive obstetric hemorrhage: Current approach to management

Obstetric Hemorrhage, its role in maternal morbidity and mortality and the importance of its diagnosis, prevention and timely management

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