Multidisciplinary Therapy of Locally Far-Advanced or Inflammatory Breast Cancer with Fixed Perioperative Sequence of Epirubicin, Vinorelbine, and Fluorouracil Chemotherapy, Surgery, and Radiotherapy: Long-Term Results

Neoadjuvant sequential epirubicin and docetaxel followed by surgery-radiotherapy and post-operative docetaxel or gemcitabine/vinorelbine combination based on primary response: a multimodality approach for locally advanced breast cancer

“…The conversion of an initially inoperable breast cancer to operable or even more, in selected cases, to conservatively operable is a major goal. Primary systemic therapy (PST) integrated into a multimodality program is the established treatment for LABC (Low et al 2004;Ardavanis et al 2006). Induction chemotherapy also has the advantages of in vivo assessment of response to therapy, delivery of drugs through intact vasculature and early initiation of PST.…”