Multidrug resistance in Salmonella enterica serovar typhi isolated from patients with typhoid fever complications in Lagos, Nigeria

Akinyemi, Kabiru Olusegun; Smith, Stella I.; Oyefolu, A O; Coker, A. O.

doi:10.1016/j.puhe.2004.04.009

Cited by 82 publications

(72 citation statements)

References 13 publications

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“…It was found that all the 25 (100%) isolates were susceptible to ciprofloxacin. This result was comparable to previous reports by Molla et al (2006) from central part of Ethiopia among isolates of sheep and goat meat, Akinyemia et al (2005) from Nigeria, from human isolates and Zelalem et al (2011), isolates of Salmonella from dairy farms in Addis Ababa. The effectiveness of drugs like ciprofloxacin could be because they are not widely used in countries like Ethiopia and other African countries (Zelalem et al, 2011).…”

Section: Discussionsupporting

confidence: 90%

“…Furthermore, Zelalem et al (2011) also indicated resistance of Salmonella isolates to commonly used antimicrobials including ampicillin, streptomycin, nitrofurantoine, kanamycine and tetracycline, with resistance rate of 100, 66.7, 58.3 and 33.3%, respectively. Similarly, previous reports from South India (Suresh et al, 2006), from Nigeria (Akinyemia et al, 2005) and from Cameroon (Akoachere et al, 2009) indicated a similar 100, over 90 and 100%, respectively resistance to ampicillin. The result of the current research also showed resistance of Salmonella isolates to commonly used antimicrobials including ampicillin, nalidixic acid and kanamycin with resistance rate of 100, 88 and 64%, respectively.…”

Section: Discussionsupporting

confidence: 75%

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Prevalence and antimicrobial susceptibility profile of Salmonella species from ready-to-eat foods from catering establishments in Jigjiga City, Ethiopia

Wolde¹,

Abate²,

Henok³

et al. 2016

Afr. J. Microbiol. Res.

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Food-borne pathogens are the leading cause of morbidity and mortality in developing countries. Changes in eating habits, mass catering, unsafe food storage conditions and poor hygiene practices are major contributing factors to food associated illnesses. In Ethiopia, the widespread habit of readyto-eat food consumption is potential cause of food borne illnesses. The present study aimed at investigating the prevalence and antimicrobial susceptibility profile of Salmonella species from readyto-eat foods from catering establishments in Jigjiga City and determining susceptibility pattern of bacterial isolates. This study aimed to assess the ready-to-eat foods Salmonella prevalence and antimicrobial resistance pattern of the isolates. In total, various food samples were collected from 120 hotels and processed to detect Salmonella presence. The ready-to-eat food samples were collected and assessed bacteriologically for Salmonella strains. A total of 120 food samples were bacteriologically evaluated. After confirmation, 25 samples (20.8%) were positive to Salmonella. A total of 5 drug resistance patterns were detected among Salmonella isolates. Out of the 25 isolates 10 (40%) were resistant to three antibiotics, 8 (28%) of the isolates were resistant to 4 of the antibiotics tested, whereas 5 (20%) were resistant to two antibiotics, only 1 (4%) isolate was resistant to 1 antibiotic but 1 (4%) isolate was resistant to five antibiotics. The lack of public sanitary facilities can be another hurdle to keep the desirable hands hygiene of the vendors. In this study, it is reported that severity of the current scenario among the hotel worker hygiene and they are the unknowingly playing role in spread of diseases like Salmonellosis.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 75%

Prevalence and antimicrobial susceptibility profile of Salmonella species from ready-to-eat foods from catering establishments in Jigjiga City, Ethiopia

Wolde¹,

Abate²,

Henok³

et al. 2016

Afr. J. Microbiol. Res.

View full text Add to dashboard Cite

show abstract

“…Secondly, either clonal spread and/or extrachromosomal genes may be potential mechanisms for increase in the level of reduced susceptibility as noticed in this study, an observation that has been well documented in literature. 4,5 The implication of high prevalence of multiple antibiotic resistance recorded in our study is that efÞ cacy of the relatively cheap empirical therapy for typhoid fever patients in Nigeria is now doubtful and thus calls for urgent attention. More importantly, the increasing trends of MDR -Salmonella enterica serovar Typhi may spread to neighbouring countries of Africa and other parts of the world particularly among the travelers returning from this region, if the unprecedented upsurge remains unchecked.…”

Section: Membersmentioning

confidence: 90%

Trends of antibiotic resistance in <i><i>Salmonella</i> enterica </i>serovar typhi isolated from hospitalized patients from 1997 to 2004 in Lagos, Nigeria

Akinyemi¹,

Coker²

2007

Indian J Med Microbiol

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“…Worldwide, the disease is mainly associated with low socio-economic status and poor hygiene. It is considered as one of the most serious infectious disease threats to public health globally with particular concern over the rapid and widespread emergence of multiple antibiotic resistance among the species [9][10][11]. According to our knowledge, the validity of Widal test has not been assessed in Libya.…”

Section: Introductionmentioning

confidence: 99%

Typhoid fever: misuse of Widal test in Libya

Zorgani

Ziglam

2014

J Infect Dev Ctries

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The worldwide gold standard of diagnosing of enteric fever depends on the isolation of Salmonella enterica serovar Typhi from a patient's bone marrow and/or blood culture. In Libya clinicians are heavily dependent on the Widal test for diagnosis of enteric fever which has been used without determining the locally appropriate threshold titer, because the laboratories lack the skilled, experienced personnel and appropriate facilities to detect and serotype Salmonella isolates. To improve the diagnosis process, clinical management and reliability of public health measures, there is an urgent need for the effective training of laboratory technicians and to provide resources to culture Salmonella species according to published guidelines. Clinicians should understand the limitations of Widal test and recognize that it cannot be expected to give a reliable diagnosis.

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Multidrug resistance in Salmonella enterica serovar typhi isolated from patients with typhoid fever complications in Lagos, Nigeria

Cited by 82 publications

References 13 publications

Prevalence and antimicrobial susceptibility profile of Salmonella species from ready-to-eat foods from catering establishments in Jigjiga City, Ethiopia

Prevalence and antimicrobial susceptibility profile of Salmonella species from ready-to-eat foods from catering establishments in Jigjiga City, Ethiopia

Trends of antibiotic resistance in <i><i>Salmonella</i> enterica </i>serovar typhi isolated from hospitalized patients from 1997 to 2004 in Lagos, Nigeria

Typhoid fever: misuse of Widal test in Libya

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