Multidrug-Resistant<i>Salmonella enterica</i>Serovar Infantis, Israel

Gal-Mor, Ohad; Valinsky, Lea; Weinberger, Miriam; Guy, Sara; Jaffe, Joseph; Schorr, Yosef Ilan; Raisfeld, Abraham; Agmon, Vered; Nissan, Israel

doi:10.3201/eid1611.100100

Cited by 75 publications

(81 citation statements)

References 10 publications

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“…It is well established on poultry farms with a tendency of clonal spread of the multidrug resistance phenotype. Clonal spread of Salmonella Infantis in poultry and poultry meat was reported in Japan (Shahada et al, 2006), Hungary (Nógrády et al, 2007), Israel (Gal-Mor et al, 2010), Italy (Dionisi et al, 2011), Germany (Hauser et al, 2012), Serbia (Rašeta et al, 2014;Velhner et al, 2014) but also in humans in Argentina (Merino et al, 2003) and Brazil (Fonseca et al, 2006). All these clonal strains were resistant to three or more antimicrobials except for Serbia, where the predominant resistance phenotype was nalidixic acid (NAL) / tetracycline (TET), while an approximate 30% of the isolates was showing resistance to ciprofloxacin (CIP), with the minimal inhibitory concentration (MIC) of > 1mg/L (Velhner et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

Salmonella spp. in poultry: a constant challenge and new insights

Velhner

Milanov

Kozoderović

2018

J Hellenic Vet Med Soc

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ABSTRACT. The knowledge about virulence mechanisms, resistance to antimicrobial agents and the biofilm formation ability of Salmonella spp. in poultry industry has been expanded over the years. However, in spite of the research efforts and significant investments to improve management systems in poultry industry, it has become evident that none of the methods applied in all stages of food production chain are 100% effective in eliminating Salmonella spp. Different serovars are manifesting different mechanisms of invasiveness which depend on their ability to invade lower zones of the lamina propria, their ability to gain accesses to parenchymatous organs and survive in macrophages. The ubiquitous nature of Salmonella spp. due to their adaptation to animal and plant hosts, as well as their survival in hostile environments and their enhanced capacity to produce biofilms, contribute to a long lasting contamination of the environment, feed and animals. The emergency and spread of antimicrobial resistances in Salmonella spp. raise additional concerns.

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Section: Discussionmentioning

confidence: 99%

Salmonella spp. in poultry: a constant challenge and new insights

Velhner

Milanov

Kozoderović

2018

J Hellenic Vet Med Soc

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“…S. Infantis has been reported in food borne outbreaks (mainly poultry products) around the world (Miller et al, 2010). Furthermore, multidrug-resistant S. Infantis has been frequently reported (Dahshan et al, 2010, Dionisi et al, 2011, Gal-Mor et al, 2010and Nogrady et al, 2012. The minimum inhibitory concentrations (MICs) of the S. Infantis strain were measured using a published protocol (Andrews, 2001) and determined to be 8 mg/L for oxytetracycline, >256 mg/L for sulfamethoxazole, and >256 mg/L for lincomycin.…”

Section: Chemicalsmentioning

confidence: 99%

Concomitant uptake of antimicrobials and Salmonella in soil and into lettuce following wastewater irrigation

Sallach

Zhang

Hodges

et al. 2015

Environmental Pollution

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“…To this day, several types of tet genes were reported in S. Infanits. In Japan and Israel the tetA gene was found in isolates from poultry [13,14]. In the epidemiologically unrelated S. Infantis, distributed evenly in two clusters obtained by pulsed fi eld gel electrophoresis, the tetA and tetB genes were found in Italy [15].…”

Section: Resultsmentioning

confidence: 97%

Characterization Of Tetracycline Resistance Of Salmonella Enterica Subspecies Enterica Serovar Infantis Isolated From Poultry In The Northern Part Of Serbia

et al. 2015

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Resistance to tetracycline was studied in Salmonella Infantis isolated from 28 poultry farms in the Northern part of Serbia (The Autonomous Province of Vojvodina). A total of 18 isolates were resistant to nalidixic acid (NAL) and tetracycline (TET). The minimal inhibitory concentration (MIC) to TET, ranged from 1-256 mg/L. Namely, 13 isolates exhibited MIC to TET at 256 mg/L, in four of the isolates, the MIC was 128 mg/L and one isolate had MIC 64 mg/L. Ten isolates were exhibiting a MIC of 1mg/L. It was evident that Salmonella Infantis had also spread to breeders and layers. In this work, we detected the tetA gene and the corresponding tetR gene (encoding the repressor protein) as well as the truncated transposon Tn1721, which are responsible for the resistance to TET. The presence of the non conjugative transposons from the conjugative plasmid has facilitated the spread of resistance to TET in Salmonella. It was concluded that higher biosecurity practice in poultry farming presents the best option to eliminate infections caused by Salmonella spp. from poultry fl ocks in Serbia. A rational use of antimicrobials is necessary to prevent any further spread of Salmonella Infantis resistant clones.

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Multidrug-ResistantSalmonella entericaSerovar Infantis, Israel

Cited by 75 publications

References 10 publications

Salmonella spp. in poultry: a constant challenge and new insights

Salmonella spp. in poultry: a constant challenge and new insights

Concomitant uptake of antimicrobials and Salmonella in soil and into lettuce following wastewater irrigation

Characterization Of Tetracycline Resistance Of Salmonella Enterica Subspecies Enterica Serovar Infantis Isolated From Poultry In The Northern Part Of Serbia

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