Multifaceted applications of ulvan polysaccharides: Insights on biopharmaceutical avenues

Shah, Saurabh; Famta, Paras; Shahrukh, Syed; Jain, Naitik; Vambhurkar, Ganesh B.; Srinivasarao, Dadi A.; Raghuvanshi, Rajeev Singh; Singh, Shashi Bala; Srivastava, Saurabh

doi:10.1016/j.ijbiomac.2023.123669

Cited by 17 publications

(4 citation statements)

References 85 publications

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“…Ulvan, a primary constituent of the Ulva cell wall, is an anionic sulfated polysaccharide and exhibits unique properties, such as its hydrophilic and hydrophobic functional groups and polyanionic nature, making it a key component in bioplastic production [102,103]. Ulvan possesses several functional groups that allow it to interact with other molecules, opening up many potential applications in different industries [104].…”

Section: Ulvanmentioning

confidence: 99%

Towards a Sustainable Circular Economy: Algae‐Based Bioplastics and the Role of Internet‐of‐Things and Machine Learning

Bin Abu Sofian,

Lim,

Manickam

et al. 2023

ChemBioEng Reviews

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The growing potential of sustainable materials such as polyhydroxyalkanoates (PHAs), polylactic acid (PLA), alginate, carrageenan, and ulvan for bioplastics production presents an opportunity to promote a sustainable circular economy. This review investigates their properties, applications, and challenges. Bioplastics derived from algae offer an environmentally friendly alternative to petroleum‐based plastics, a shift of paramount importance to society due to the escalating environmental concerns associated with traditional plastics. The role of the internet‐of‐things (IoT) and machine learning in refining these bioplastics' production and development processes is emphasized. IoT monitors cultivation conditions, data collection, and process control for more sustainable production. Machine learning can enhance algae cultivation, increasing the supply of raw materials for algal bioplastics and improving their efficiency and output. The study results indicate the promise of algae‐based bioplastics, IoT, and machine learning in fostering a more environmentally sustainable future. By harnessing these advanced technologies, optimization of bioplastic production is possible, potentially revolutionizing the materials industry and addressing existing challenges toward achieving a sustainable circular economy.

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Section: Ulvanmentioning

confidence: 99%

Towards a Sustainable Circular Economy: Algae‐Based Bioplastics and the Role of Internet‐of‐Things and Machine Learning

Bin Abu Sofian,

Lim,

Manickam

et al. 2023

ChemBioEng Reviews

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“…Ulvan, a marine sulfated heteropolysaccharide found in green algae, is composed of rhamnose, xylose, sulfate, d-glucuronic acid, and l-iduronic acid. Ulvan is utilized widely in biomedical, pharmaceutical, and cosmetic applications because of its great biocompatibility and broad bioactivities, which include antibacterial, immunostimulating, antioxidant, and anti-inflammatory effects [ 179 , 180 ]. Hydrophilic ulvan can produce hydrogel in the presence of ions (such as B + and Ca 2+ ) at a basic pH, and their sulfate and carboxylate groups have a high water-absorption capacity [ 179 ].…”

Section: Application Of Marine Organisms-derived Polysaccharide Nanom...mentioning

confidence: 99%

Marine biomaterials in biomedical nano/micro-systems

Wang,

Chen,

Wang

et al. 2023

J Nanobiotechnol

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Marine resources in unique marine environments provide abundant, cost-effective natural biomaterials with distinct structures, compositions, and biological activities compared to terrestrial species. These marine-derived raw materials, including polysaccharides, natural protein components, fatty acids, and marine minerals, etc., have shown great potential in preparing, stabilizing, or modifying multifunctional nano-/micro-systems and are widely applied in drug delivery, theragnostic, tissue engineering, etc. This review provides a comprehensive summary of the most current marine biomaterial-based nano-/micro-systems developed over the past three years, primarily focusing on therapeutic delivery studies and highlighting their potential to cure a variety of diseases. Specifically, we first provided a detailed introduction to the physicochemical characteristics and biological activities of natural marine biocomponents in their raw state. Furthermore, the assembly processes, potential functionalities of each building block, and a thorough evaluation of the pharmacokinetics and pharmacodynamics of advanced marine biomaterial-based systems and their effects on molecular pathophysiological processes were fully elucidated. Finally, a list of unresolved issues and pivotal challenges of marine-derived biomaterials applications, such as standardized distinction of raw materials, long-term biosafety in vivo, the feasibility of scale-up, etc., was presented. This review is expected to serve as a roadmap for fundamental research and facilitate the rational design of marine biomaterials for diverse emerging applications. Graphical Abstract

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“…They are rich sources of proteins, lipids, carbohydrates, polysaccharides, polyphenols, essential amino acids, carotenoids, vitamins (vitamin A, B 12 , B 9 , B 2 , B 1 , C, E, D, and K), minerals (iodine (I), iron (Fe), potassium (K), zinc (Zn), copper (Cu), magnesium (Mg), and calcium (Ca)), essential fatty acids, and dietary fiber [3][4][5][6][7][8]. Important polysaccharides from marine algae include sulfated galactans, namely carrageenans, agarose, alginate, and agar from red algae, ulvans from green algae, and alginates, fucoidans, and laminarans of brown algae [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

An Update on the Chemical Constituents and Biological Properties of Selected Species of an Underpinned Genus of Red Algae: Chondrus

Park,

Sharma,

Lee

2024

Marine Drugs

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Macroalgae, particularly red seaweeds, have attracted significant attention due to their economic and health benefits. Chondrus, a red algae genus, despite its economic importance, seems to be undervalued. Among all its species, Chondrus crispus has been meticulously documented for its biological properties, and little is known about other species. No comprehensive review of the biological properties of this genus has been acknowledged. Thus, this review aimed to summarize the available information on the chemical constituents and biological properties of a few selected species, including Chondrus crispus, Chondrus ocellatus, Mazzaella canaliculata, and Chondrus armatus. We compiled and discovered that the genus is offering most of the important health-promoting benefits evidenced from in vitro and in vivo studies focused on antimicrobial, immunomodulation, neuroprotection, anti-atopic, anti-inflammatory, anti-viral, anti-diabetic, cytoprotective, antioxidant, anti-coagulation, nephroprotective, anti-tumor, and anti-venom activity, which speaks about the potential of this genus. Data on clinical studies are limited. Further, around 105 chemical constituents have been reported from Chondrus spp. Given its significance, further investigation is warranted, in the form of meticulously planned cell, animal, and clinical studies that concentrate on novel health-enhancing endeavors, in order to unveil the full potential of this genus. The review also outlines challenges and future directions.

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Multifaceted applications of ulvan polysaccharides: Insights on biopharmaceutical avenues

Cited by 17 publications

References 85 publications

Towards a Sustainable Circular Economy: Algae‐Based Bioplastics and the Role of Internet‐of‐Things and Machine Learning

Towards a Sustainable Circular Economy: Algae‐Based Bioplastics and the Role of Internet‐of‐Things and Machine Learning

Marine biomaterials in biomedical nano/micro-systems

An Update on the Chemical Constituents and Biological Properties of Selected Species of an Underpinned Genus of Red Algae: Chondrus

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