Multifocal Colonic Lesions Detected by 18F-FDG PET/CT: Correlation with Histopathology and Gross Specimen

Kim, Dae Weung; Jung, Sang Ah; Park, Soon Ah; Kim, Chang Guhn

doi:10.1007/s13139-010-0030-3

Cited by 2 publications

(1 citation statement)

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“…However, as in two of our patients and in a case reported by Kim et al . the SUVmax of adenomatous lesion on 18F-FDG PET/CT can be higher than the primary tumor and cannot make the distinction between benign and malignant lesions [9].…”

Section: Discussionmentioning

confidence: 99%

The potential role of 68Ga-FAPI-04 PET/CT for screening malignancy in suspected colonic lesions

Fenercioğlu

Beyhan

Şahin

et al. 2023

Nuclear Medicine Communications

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Aim Benign colonic lesions like tubular adenoma may show intense uptake on F-18-FDG PET/CT and can be mistaken for malignancy. In this study, we evaluated the role of 68Ga-FAPI-04 PET/CT for discriminating the benign and malignant colonic lesions. Methods Forty patients with diagnosis of colorectal cancer who had undergone 18F-FDG-PET/CT and 68Ga-FAPI-04 PET/CT for initial staging were retrospectively analyzed. The unexpected foci of uptake in colon on 18F-FDG PET/CT were compared with 68Ga-FAPI-04 PET/CT with lesion and background SUVmax. Results The primary colorectal lesion SUVmax on both PET/CTs was similar. A total of 9 incidental colon lesions in 7 patients were detected showing intense 18F-FDG uptake and no 68Ga-FAPI-04 uptake. All of the lesions were consistent with tubular adenoma histopathologically. Conclusion 68Ga-FAPI PET/CT may have a crucial role for discrimination of benign and malignant colonic lesions and avoid the unnecessary interventions and extended surgeries in patients with colorectal cancer.

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Section: Discussionmentioning

confidence: 99%