Multifocal Electroretinograms in Normal Subjects

Nagatomo, Akiko; Nao‐i, Nobuhisa; Maruiwa, Futoshi; Arai, Mikki; Sawada, Atsushi

doi:10.1016/s0021-5155(97)00118-4

Cited by 34 publications

(21 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is in good agreement with previous studies for the same or similar parameters using ring average analyses [17,19,27,37,39]. Previous studies have demonstrated that the amplitude decline and latency increase with age could not be explained entirely by changes in optical factors (such as age-related change in pupil size and optical transmission of the lens), and, therefore, neural or metabolic factors should be considered [19,27,48].…”

Section: Discussionsupporting

confidence: 92%

“…Nagamoto et al [39] (using lower mean luminance and fewer stimulating areas) demonstrated larger N1P1 mfERG amplitude in the upper retina, but they did not estimate the effect of age. Similarly, higher amplitudes of the pattern ERG were obtained from stimulation of the upper hemiretina [61].…”

Section: Hemifield Differences Associated With Agementioning

confidence: 94%

“…There have been no previous studies to examine such an effect. In general, P1 implicit times from the nasal retina were found to be longer than the ones from the temporal retina [39,42,47]. The source of this difference is unclear.…”

Section: Hemifield Differences Associated With Agementioning

confidence: 99%

“…As might be expected from full-field ERG analyses, it is now widely accepted that some of the mfERG components demonstrate a relationship with age [17,19,27,[37][38][39]48]. However, most of these studies were based on limited sample sizes and limited age ranges [17,27,37,38].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Senescence of human multifocal electroretinogram components: a localized approach

Tzekov

Gerth

Werner

2004

Graefe's Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

Background-Previous studies have shown significant age-related changes in the first-order kernel of multifocal ERG (mfERG) responses. All of these reports were based upon ring averages across the retinal field. This study was carried out to determine age-related changes in the localized response and localized variability in the mfERG parameters: N1P1 amplitude, scalar product and implicit time of P1.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Hemifield Differences Associated With Agementioning

confidence: 94%

Section: Hemifield Differences Associated With Agementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Senescence of human multifocal electroretinogram components: a localized approach

Tzekov

Gerth

Werner

2004

Graefe's Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Amplitude density (nV/deg 2 ) represents the amplitudes for each grouping adjusted for the distance angle of the stimulus element, giving a more accurate view of the actual response amplitudes of each group. 23 To construct the two and three-dimensional plots the mean of amplitude density was used. 9 The criteria for the normal controls included in the study were an age of over 18 years, visual acuity of 1.0 with or without correction and contact lens tolerance for both groups.…”

Section: Slo-mferg Results In Patients With Macular Holes G Rudolph Ementioning

confidence: 99%

Scanning laser ophthalmoscope-evoked multifocal ERG (SLO-mfERG) in patients with macular holes and normal individuals

Rudolph

Kalpadakis

Bechmann

et al. 2003

Eye

View full text Add to dashboard Cite

Aims A scanning laser ophthalmoscope (SLO) has been used for multifocal electroretinography (mf ERG) measurements under simultaneous fundus monitoring. The aim of this study was to prove if the SLOmfERG measurement reflects reliably the clinically registered underlying disease, and to demonstrate the importance of its main advantage, fixation monitoring. Methods In all, 10 patients with macular hole stage II/III were included in the study, and 19 normal individuals served as the control group. The mf ERG device was combined with an SLO, which was used both as a stimulus and trigger unit as well as a fundusmonitoring system. Monitoring of the fundus was guaranteed by an infrared laser (780 nm). The stimulus matrix consisted of 61 hexagonal elements, covering 241 of the posterior pole. We examined both, patients with macular holes and healthy individuals. Results Compared to normal controls, patients with a macular hole (Gass stage III) showed a significant decrease in response density in the centre of the stimulus array, which correlated well with the morphological alteration observed by clinical examination. However, variation of response density of the central hexagonal area has been proved to be high. Conclusions SLO-mfERG is a feasible and reliable new technique to investigate macular function under simultaneous fundus control. The main advantage is that control of fixation can be used in order to obtain more reliable results that correlate well with visible fundus abnormalities such as in patients with macular holes. However, further investigations have to be performed in order to overcome sufficiently the problem of fixation instability.

show abstract

Multifocal electroretinogram: age-related changes for different luminance levels

Gerth

Garcia

et al. 2002

Graefe's Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

show abstract

Multifocal Electroretinograms in Normal Subjects

Cited by 34 publications

References 6 publications

Senescence of human multifocal electroretinogram components: a localized approach

Senescence of human multifocal electroretinogram components: a localized approach

Scanning laser ophthalmoscope-evoked multifocal ERG (SLO-mfERG) in patients with macular holes and normal individuals

Multifocal electroretinogram: age-related changes for different luminance levels

Contact Info

Product

Resources

About