Multifocal small bowel stromal tumours presenting with peritonitis in an HIV positive patient

Mansoor, Ebrahim

doi:10.1016/j.ijscr.2014.03.005

Cited by 7 publications

(7 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These were all undiagnosed primary GISTs tumours. In one patient the small intestinal GIST was associated with hepatic metastases [9] , in the other two cases small bowel GISTs were multifocal [26,29] . In all the other 19 patients there was a primary localized single GIST.…”

Section: Discussionmentioning

confidence: 90%

“…However GIST perforation seems to occur more frequently in the small bowel compared to other anatomic sites [35] . Our literature search revealed 21 cases of acute abdomen with diffuse or localized peritonitis caused by spontaneous perforation of small intestine GISTs ( Table 1 ) [9–29] . Two more cases are reported in the case-series of Mansour and Coll [8] .…”

Section: Discussionmentioning

confidence: 99%

“…Few GISTs manifest as abdominal emergencies, such as GI haemorrhage, intestinal obstruction, or tumour perforation [7,8] . Although acute abdomen due to GIST perforation into the peritoneal cavity is rare, a few cases of peritonitis caused by perforation of small-intestinal GISTs have been reported in the literature [8–29] . Together with a review of the published cases, here we report a case of an elderly patient with acute abdomen due to spontaneous perforation of a GIST located in the jejunum.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumour of the small intestine: A case report and a literature review

Alessiani

Gianola²,

Rossi

et al. 2015

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

HighlightsEmergency presentation of a GIST is not uncommon and one of its manifestations is acute abdome.The cases described in the literature are the tip of the iceberg and spontaneous rupture or perforation of GISTs are a far more frequent first presentation of this rare tumour.The jejunum was the more common location of perforation compared to the ileum.Emergency surgery is mandatory and should achieve radical resection.

show abstract

Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumour of the small intestine: A case report and a literature review

Alessiani

Gianola²,

Rossi

et al. 2015

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

show abstract

“…Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, 60% involving the stomach and 30% in the small bowel; 25% of GISTs are asymptomatic and accidentally discovered, 10–20% of them reveal metastatic disease upon initial diagnosis [27]. As far as we know, only few cases of GIST in HIV positive patients have been reported.…”

Section: Discussionmentioning

confidence: 99%

Rapid emergence of cryptococcal fungemia, Mycobacterium chelonae vertebral osteomyelitis and gastro intestinal stromal tumor in a young HIV late presenter: a case report

et al. 2018

View full text Add to dashboard Cite

BackgroundHighly active antiretroviral therapy has significantly changed the natural history of HIV infection, leading to a dramatic reduction of HIV-related morbidity and mortality. Late Presenters, Very Late Presenters and AIDS presenters still represent, also in Europe, including Italy, a huge challenge in terms of diagnostic and therapeutic management.Case presentationA 35-year-old male with a history of fever and back pain. HIV test resulted positive with a high HIV Viral Load and a very low T-CD4 number of cells (5 cells/mm3). Imaging investigations revealed multiple vertebral and pulmonary lesions together with abdominal and thoracic lymphadenopathy. Blood cultures were positive for Cryptococcus neoformans and for Staphylococcus haemolyticus.Lymphnode biopsy resulted positive in PCR for Non-Tuberculosis Mycobacteria (Mycobacterium chelonae). A gastric biopsy also revealed a GIST. The patient also had CMV DNA positive. Although we performed antiretroviral therapy and specific-therapies for each disease, he was transferred to intensive care unit where he died due to an Acute Respiratory Distress Syndrome.ConclusionThe reported case is unusual due to the relevant number of opportunistic diseases (both infectious and tumoral) emerging not long after the HIV infection had been diagnosed.Late presenters HIV patients and AIDS presenters still represent a challenge, which is often too complex for clinicians to deal with. In spite of proper management, the risk of suboptimal results cannot be excluded.Electronic supplementary materialThe online version of this article (10.1186/s12879-018-3573-z) contains supplementary material, which is available to authorized users.

show abstract

“…GISTs usually appear as solitary well-circumscribed masses [1], [2], [4]. Sporadic multifocal GISTs in adults represent only 11% of all multifocal diseases [5], [6]. The grading of malignancy is based on the assessment of the tumor size, the mitotic index, and the tumor localization [1], [7].…”

Section: Introductionmentioning

confidence: 99%

Multifocal gastrointestinal stromal tumor: A case report with CT, surgical, and histopathologic correlation

Brogna¹,

Imbriani²,

Forte³

et al. 2019

Radiology Case Reports

View full text Add to dashboard Cite

Mutifocal gatrointestinal stromal tumors (GISTs) are rare conditions that are usually associated with other syndromes or reported in pediatric cases. The sporadic form represents only 11% of GISTs. The imaging features on a contrast-enhanced computed tomography examination, surgery and histopathology of a rare case of a sporadic multifocal small bowel GISTs in an emergency setting are described. This case highlights how GISTs appearances on an imaging computed tomography may vary. Radiologists can have difficulty in defining the point of origin of large lesions. In our case, laparotomy open surgery was mandatory to figuring out the correct diagnosis.

show abstract

Multifocal small bowel stromal tumours presenting with peritonitis in an HIV positive patient

Cited by 7 publications

References 7 publications

Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumour of the small intestine: A case report and a literature review

Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumour of the small intestine: A case report and a literature review

Rapid emergence of cryptococcal fungemia, Mycobacterium chelonae vertebral osteomyelitis and gastro intestinal stromal tumor in a young HIV late presenter: a case report

Multifocal gastrointestinal stromal tumor: A case report with CT, surgical, and histopathologic correlation

Contact Info

Product

Resources

About