The reason for the self-similarity property of complex network is still an open issue. In this paper, we focus on the influence of degree, betweenness, and coreness on self-similarity of complex network. Some nodes are removed from the original network based on the definitions of degree, betweenness, and coreness in the ascending and descending order. And then, some new networks are obtained after removing nodes. The self-similarities of original network and new networks are compared. Moreover, two real networks are used for numerical simulation, including a USAir network and the yeast protein interaction (YPI) network. The effects of the three statistical variables on the two real networks are considered. The results reveal that the nodes with large degree and betweenness have great effects on self-similarity, and the influence of coreness on self-similarity is small.