Multifunctional hydrogel bioscaffolds based on polysaccharide to promote wound healing: A review

Ding, Chuanbo; Liu, Xinglong; Zhang, Shuai; Sun, Shuwen; Yang, Jiali; Chai, Guodong; Wang, Ning; Ma, Shuang; Ding, Qiteng; Liu, Wencong

doi:10.1016/j.ijbiomac.2024.129356

Cited by 10 publications

(1 citation statement)

References 108 publications

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“…As one of the major challenges facing the global healthcare system, millions of cutaneous wounds occur each year as a result of surgery, burns, and accidental trauma [ 1 ]. Although the skin can regenerate to a certain extent, severe skin defects cannot heal themselves [ 2 , 3 ] and are more susceptible to infection by viruses, bacteria, and pathogenic microorganisms, resulting in skin redness, wound rupture, suppuration and even death [ 4 ]. To date, a wide variety of wound dressings, including gauze [ 5 ], hydrogels [ 6 , 7 ], foams [ 8 ], and nanofibers [ 9 , 10 ], have been developed to treat various types of wounds [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Hydrogel Wound Dressings Accelerating Healing Process of Wounds in Movable Parts

Yu,

Wei,

Yang

et al. 2024

IJMS

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Skin is the largest organ in the human body and requires proper dressing to facilitate healing after an injury. Wounds on movable parts, such as the elbow, knee, wrist, and neck, usually undergo delayed and inefficient healing due to frequent movements. To better accommodate movable wounds, a variety of functional hydrogels have been successfully developed and used as flexible wound dressings. On the one hand, the mechanical properties, such as adhesion, stretchability, and self-healing, make these hydrogels suitable for mobile wounds and promote the healing process; on the other hand, the bioactivities, such as antibacterial and antioxidant performance, could further accelerate the wound healing process. In this review, we focus on the recent advances in hydrogel-based movable wound dressings and propose the challenges and perspectives of such dressings.

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Section: Introductionmentioning

confidence: 99%

Hydrogel Wound Dressings Accelerating Healing Process of Wounds in Movable Parts

Yu,

Wei,

Yang

et al. 2024

IJMS

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Sprayable Nanocomposites Hydrogel for Wound Healing and Skin Regeneration

Li,

Luo,

et al. 2024

Adv Healthcare Materials

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Wound management remains a critical challenge worldwide and imposes a huge financial burden on every nation. Hydrogels are promising for biomedical applications because of their extracellular matrix (ECM) like structure, good biocompatibility and multifunctional bioactivity. However, the poor mechanical properties and inconvenient operation of traditional hydrogels make it difficult to meet the complex and multifaceted needs of clinical practice. In recent years, the multifunctional nanocomposites hydrogel with especially sprayable feature have shown enhanced mechanical properties and facile operation, which enable their huge clinical applications value. A unique and powerful nanocomposite hydrogels (NCH) platform is developed by combining the many advantages of nanomaterials and hydrogels, which can achieve efficient trauma repair. This work reviews important advances on the preparation, functions and applications of sprayable NCH platforms. The challenges and future trends in the field with the aim of providing researchers with clarity on the past, present, and future of the emerging field of sprayable NCH are also proposed in detail.

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Nanoengineered Tools in the Treatment of Diabetic Wounds: a Review on Next-Generation Multidimensional Therapeutic Approaches

Sanku,

Ahirwar,

Pinapati

et al. 2024

BioNanoSci.

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Multifunctional hydrogel bioscaffolds based on polysaccharide to promote wound healing: A review

Cited by 10 publications

References 108 publications

Hydrogel Wound Dressings Accelerating Healing Process of Wounds in Movable Parts

Hydrogel Wound Dressings Accelerating Healing Process of Wounds in Movable Parts

Sprayable Nanocomposites Hydrogel for Wound Healing and Skin Regeneration

Nanoengineered Tools in the Treatment of Diabetic Wounds: a Review on Next-Generation Multidimensional Therapeutic Approaches

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