Multifunctional Mesoporous ZnO@BMMs with Strong Fluorescence and High Loading Capacity for Controlled Drug Delivery

Abstract

Multifunctional mesoporous ZnO@BMMs were prepared via a facile and reliable post treatment, in which the influence of various parameters, including the amount of ZnCl 2 doping, the different anions of the zinc salt, and the roasting temperature, on their structure, properties, and fluorescence performance were investigated by XRD, SEM, TEM, EDS, DLS, XPS, BET, PL, UV, and TGA/DTG. The drug loading and release performance was explored by using ibuprofen (IBU) as a model drug. The results showed that the ZnO@BMMs before drug- [a]

Multifunctional Mesoporous CDQs/BMMs with Strong Fluorescent Property and Sustained Drug Releasing Performance

“…The drug delivery behaviors of the selected CBI as a drug carrier were shown in Figure . As can be seen in Figure A, the IBU loading capacity of CBI rapidly reached 131.4 mg g −1 and then run up to 154.3 mg g −1 , indicating that CBI had the fast adsorption ability, due to the better IBU‐diffused property in the bimodal mesoporous structures . Figure B showed the IBU‐released behaviors of CBI, which well fitted the exponential equation with high coefficiency of R 2 =0.985, as follows: …”

“…Interestingly, we found that the MSE method was very useful to remove of CTAB from intermediate than MSI and MSA methods. Overall, these observations suggest the successful introduction of CQDs to BMMs …”

“…All samples clearly exhibited the characteristic diffractive peak ( 100 ) at 2θ of around 1.7–2.0°, indicating the presence of the ordered mesopore structure . The position of diffractive peak ( 100 ) for doped‐CQDs BMMs shifted to lower angle, specifically, from 2.02° for BMMs (Figure A–a) to 1.81° for CBI (Figure A–b), CBE (Figure A‐c), and CBA (Figure A‐d) (detailed CBI, CBE, CBA in experimental section of Supporting Information), corresponding to d space values of from 4.37 to 4.87 nm, meanwhile, the SEM image of CBI in Figure A(inset) presented the nanoscale spherical morphology with an average diameter of about 25 nm, similar to that of traditional BMMs . The HRTEM image of CBI in Figure B showed worm‐like mesopores of around 2 nm and obvious CQDs particles in size of about 5 nm with the lattice spacing of 0.21 nm, similar to the mentioned‐above results in the CQDs aqueous solution (as shown in Figure D).…”

“…As can be seen, the weight loss procedures could be divided four stages. The first one at temperature 25–200 °C presented the weight loss of 2.0 wt % for BMMs, 2.0 wt% for CBI and 0.5 wt % for CTAB, which was attributed to removal of physisorbed water or residual solvent . In the second stage of temperature range 200–320 °C, the weight loss of BMMs, CBI, CTAB was around 0.5, 18.0, and 96.1 wt %, respectively, corresponding to dehydroxylation in BMMs, residual CTAB in CBI, and almost completed decomposition of CTAB.…”

Incorporation of Anatase TiO2 to Highly Porous Silica (BMMs) for Photo‐Degradation of Alizarin Red Dye in Aqueous Solution

“…While, the ZnO/BMMs composite was successfully synthesized via a facile and reliable post treatment, which could be used as a carrier for ibuprofen delivery, showing high loading capacity (around 250 mg/g) and an excellent sustained release behavior along with strong fluorescence. [25,26] These results demonstrated that BMMs would be a good selection as a support. Alizarin red dye (1,2-dihydroxy-9,10-anthraquinonesulfonic acid sodium salt, C 14 H 7 NaO 7 S, abbreviated as AR), as an industrially important synthetic dye from anthraquinone family, is widely used in textile industries since ancient times.…”