Multilayer Structures of Self‐Assembled Gold Nanoparticles as a Unique SERS and SEIRA Substrate

Abstract

Metallic multilayer structures consisting of self-assembled nanoparticles are prepared by successive immersion of a functionalized glass substrate in a gold colloidal suspension, and are characterized by UV/Vis spectroscopy and atomic force microscopy. The ability of the thin film to concomitantly enhance the Raman and IR signals of an adsorbed molecule is evaluated and a detailed analysis of the recorded spectra is provided, which emphasizes the capability of these complementary methods to provide information about the adsorbed species. This unique surface-enhanced Raman spectroscopy (SERS) and surface-enhanced infrared absorption (SEIRA) substrate could be further used for applications in the elucidation of the structure of a great variety of adsorbed samples.

Towards enhanced optical sensor performance: SEIRA and SERS with plasmonic nanostars

“…12 To date, substrates capable of simultaneously enhancing Raman and IR signals were demonstrated for silver nanorod arrays, 13 gold thin-film electrodes, 14 gold nanoshell arrays 15 and multilayer structures of self-assembled gold nanospheres. 16 In the present study, this was shown for the first time using in-situ prepared gold nanostars (AuNSts). Two mechanisms predominantly contribute to the enhancement observed both in SEIRAS and SERS, namely electromagnetic enhancement due to the high electric field strength surrounding the nanoparticles, and chemical enhancement resulting from chemical interactions between the analyte and the nanoparticles.…”

Folate-based single cell screening using surface enhanced Raman microimaging

“…54 Slight intensity modification and frequency shifts in the nanovector spectrum with respect to the bulk are ascribed to the gold Np surface enhanced infrared absorption effect. 55 Titration experiments using the Coomassie Brilliant Blue (CBB) dye allowed for a quantitative estimation of the number of folate molecules bound to the single Np. 56 The result shows an average number of 1900 ± 200 folate molecules (see section S3 of the ESI †).…”

Chromatographic paper embedded with silver nanostructure as a disposable substrate for surface‐enhanced Raman spectroscopy and catalytic reactor

“…Although successful in desirable high‐resolution features, these routes usually rely heavily on a sophisticated and costly instrument and are unfortunately encumbered with several fundamental limitations, such as difficulty in fabrication of stacked 3D structures and compromised spatial resolution at approximately 10 nm. Relative the to top‐down approach, many wet‐chemistry methods have been extensively utilized in the fabrication of large‐scale 3D SERS‐active substrate, like metal cylindrical nanotubes, conical nanotubes, nanoparticles, and nanowires, presenting the promising results in transforming SERS to routine chemical analysis in research lab and in fieldwork outside . Further chemical modification and metallization on cellulose network reinvigorates this foldable device to many novel functions and applications, propelling it to another dimension to the potential of disposable devices for advanced diagnostics and therapeutics in clinic trial and environmental monitoring.…”

“…Relative the to top-down approach, many wet-chemistry methods have been extensively utilized in the fabrication of large-scale 3D SERS-active substrate, like metal cylindrical nanotubes, conical nanotubes, nanoparticles, and nanowires, presenting the promising results in transforming SERS to routine chemical analysis in research lab and in fieldwork outside. [26][27][28] Further chemical modification and metallization on cellulose network reinvigorates this foldable device to many novel functions and applications, propelling it to another dimension to the potential of disposable devices for advanced diagnostics and therapeutics in clinic trial and environmental monitoring. Here we report a SERS approach on Ag-embedded chromatograph paper prepared by electroless deposition, which reinforces the ability of chemical identification and analysis without extra labeling or plugging to high voltage supply.…”