2005
DOI: 10.1097/01.brs.0000188267.66847.bf
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Multilevel Spinal Growth Modulation With an Anterolateral Flexible Tether in an Immature Bovine Model

Abstract: Given adequate bony fixation, a flexible lateral spinal tether can affect growth modulation. This technique of growth modulation may serve as a future fusionless method of correction in a growing patient with scoliosis.

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Cited by 67 publications
(27 citation statements)
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References 24 publications
(22 reference statements)
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“…9 Mechanical alteration of spinal growth with an "internal brace" placed on the convexity of the curve has been proposed as an attractive alternative to arthrodesis. 10 Various investigators have experimented with spinal growth modulation to either correct spinal deformities 11,12 or to create deformities in animal models [13][14][15][16] ; however, few studies have evaluated the resulting condition of the intervertebral disc and growth plate. Biochemical and histologic analyses of these tissues need to be performed to predict their function once the "internal brace" has been removed.…”
mentioning
confidence: 99%
“…9 Mechanical alteration of spinal growth with an "internal brace" placed on the convexity of the curve has been proposed as an attractive alternative to arthrodesis. 10 Various investigators have experimented with spinal growth modulation to either correct spinal deformities 11,12 or to create deformities in animal models [13][14][15][16] ; however, few studies have evaluated the resulting condition of the intervertebral disc and growth plate. Biochemical and histologic analyses of these tissues need to be performed to predict their function once the "internal brace" has been removed.…”
mentioning
confidence: 99%
“…The extent of scoliosis creation was however modest at 10°± 6°but satisfactory in comparison to the extent of deformity induction by other growth modulation devices. Newton et al had achieved a 11°± 2°scoliosis and 16°± 2°kyphosis using a flexible untensioned anterolateral tether in a porcine model [17] and a 12°± 58 scoliosis and 5°± 68 kyphosis in an immature bovine model [18]. Driscoll et al used a novel anterolateral device to compress the vertebral body growth plate without bridging the disc in an immature porcine model.…”
Section: Discussionmentioning
confidence: 98%
“…Conventional large animal scoliosis models are based on asymmetric spinal tethering with ribs ligation and/or resection [11][12][13][14][15][16][17]. Methods with minimal violation of the spinal elements have recently been developed, however, they still violate the thoracic cavity and require a long observation period to obtain the deformity [16][17][18][19]. The length and size of the spine obtained after deformity creation is also taller than in human early onset scoliosis.…”
Section: Th Odent (And)mentioning
confidence: 99%