Multilocular cystic renal cell carcinoma a diagnostic dilemma: A case report in a 30-year-old woman

Abstract

Multilocular cystic renal cell carcinoma (MCRCC), also known as multilocular clear cell renal cell carcinoma (RCC), is a rare cystic tumor of the kidney with an excellent outcome. It occurs in about 3.1-6% of the conventional RCC. It is usually included in the group of tumors of undetermined malignant potential with low nuclear grade. We present a case of MCRCC in a 30-year-old female patient presenting incidentally as an apparently benign-looking multicystic space occupying lesion in the upper pole of right kidney. Right-sided simple nephrectomy was performed, and on histopathologic examination it was found to be MCRCC, stage 1 with Fuhrman nuclear grade 1. Immunohistochemistry with epithelial membrane antigen and vimentin confirmed the diagnosis.

Magnetic Resonance Imaging Findings of Multilocular Cystic Renal Cell Carcinoma and Clinical-pathologic Comparison

“…One patient (10%) had Bosniak type II cyst and no Patients usually present with non-specific symptoms similar to other types RCC, such as low back pain and hematuria (13). In our study, tumor size, gender distribution, clinical symptoms, tumor lateralization, Fuhrman grade and Tumour, Node, Metastasis stage were found to be similar with the literature (11,14,17). Complete resection of the renal cyst was performed in all patients.…”

Multilocular cystic renal cell carcinoma of low malignant potential- A rare case report

“…Multilocular cystic renal cell carcinoma of low malignant potential (MCRCC) has a very low incidence of < 2% and first reported by Perlmann in 1928 and named it as lymphangiohemangioma. 1 Tumor has a low incidence accounts for about 1-2% of all renal neoplasms 1 and about 3.1 to 6% of clear cell RCC as per a study done by Chowdhary et al 1,2 They have been found patients with a mean age of 51 years and affects individuals of the age group 20 to 76. 1,2 The males are more commonly affected than females with a male to female ratio of 3:1.…”

“…1 Tumor has a low incidence accounts for about 1-2% of all renal neoplasms 1 and about 3.1 to 6% of clear cell RCC as per a study done by Chowdhary et al 1,2 They have been found patients with a mean age of 51 years and affects individuals of the age group 20 to 76. 1,2 The males are more commonly affected than females with a male to female ratio of 3:1. 3 The 2004 WHO classification recognizes MCRCC as a rare variant of clear cell RCC with a good prognosis.…”

“…It occurs in about 3.1-6% of the conventional RCC. [1][2][3] It is usually included in the group of tumors of undetermined malignant potential with low nuclear grade. Adult patients are eight times more likely to be female and most often present with flank mass, abdominal pain, or hematuria.…”

Multilocular cystic renal cell carcinoma: A case report and review of the literature

“…and its prognosis is relatively better compared with that of other malignant kidney tumors (6). The age of patients at diagnosis is >30 years, with the mean age >55 years (6,7). The morbidity increases gradually with advancing age.…”