COVID-19 is a viral disease that infects the lower airways, causing severe acute respiratory syndrome
(SARS) and fatal pneumonia. The ripple effect of the COVID-19 outbreak has created serious problems
in the healthcare systems of many countries and had far-reaching consequences for the global economy. Thus,
effective control measures should be implemented for this coronavirus infection in the future. The ongoing episode
of the SARS-CoV-2 sickness, COVID-19, in China, and the subsequent irregular spread of contamination
to different nations, has alarmed the clinical and academic community primarily due to the deadly nature
of this disease. Being a newly identified virus in the viral classification and having the highest mutation rate,
rapid therapeutics are not readily available for treating this ailment, leading to the widespread of the disease
and causing social issues for affected individuals. Evidence of Ayurveda and traditional Chinese medicine
(TCM) has been found in ancient civilizations, such as those of the Hindus, Babylonians, Hebrews, and Arabs.
Although TCM and Ayurvedic herbs do not promise to be very effective treatments for this pandemic, they
can reduce infectivity and virulence by enhancing immunity and showing effectiveness in rehabilitation after
COVID-19 disease. Thus, they could be used as sources of inhibitor molecules for certain phenomena, such as
viral replication, attachment to the host, 3CL protease inhibition, 3a ion channel inhibitors, and reverse transcription
inhibition. Medicinal plants from TCM and Ayurveda and their biologically active phytoconstituents
can effectively modulate the targets and pathways relevant to inflammation and immune responses in human
bodies. The present review analyzes the role of certain TCM and Ayurvedic medicinal plants in healing
COVID-19 infection. Medicinal plants such as Glycyrrhiza glabra (licorice), Curcuma longa (turmeric), and
Zingiber officinale (ginger) are regarded as the main antiviral herbs. Their extracts and individual bioactive
compounds could be used as potential substances for developing remedies to prevent or cure the coronavirus
disease. Generally, antiviral phytochemicals obtained from natural sources are considered potent candidates
for fighting COVID-19 infection and rehabilitation after it.