Multimodal Nonlinear Microscopy by Shaping a Fiber Supercontinuum From 900 to 1160 nm

Liu, Yuan; Tu, Haohua; Benalcazar, Wladimir A.; Chaney, Eric J.; Boppart, Stephen A.

doi:10.1109/jstqe.2011.2168559

Cited by 36 publications

(16 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, if the bandwidth is divided into 3 segments of equal optical frequency range, each segment can then be “locally” compressed to the time of its own central frequency wavelength within the limit of adjacent-pixel phase variation (Fig. 2b, colored vertical arrows in the time domain) [24]. In other words, the local compression of the spectral segments expands the dynamic range of the pulse shaper without affecting the coherence assessment, as long as the converged iteration toward transform-limited pulse compression can be demonstrated for all segments.…”

Section: Methodsmentioning

confidence: 99%

Suppressing Short-Term Polarization Noise and Related Spectral Decoherence in All-Normal Dispersion Fiber Supercontinuum Generation

Liu

Zhao

Lyngsø

et al. 2015

J. Lightwave Technol.

Self Cite

View full text Add to dashboard Cite

The supercontinuum generated exclusively in the normal dispersion regime of a nonlinear fiber is widely believed to possess low optical noise and high spectral coherence. The recent development of flattened all-normal dispersion fibers has been motivated by this belief to construct a general-purpose broadband coherent optical source. Somewhat surprisingly, we identify a large short-term polarization noise in this type of supercontinuum generation that has been masked by the total-intensity measurement in the past, but can be easily detected by filtering the supercontinuum with a linear polarizer. Fortunately, this hidden intrinsic noise and the accompanied spectral decoherence can be effectively suppressed by using a polarization-maintaining all-normal dispersion fiber. A polarization-maintaining coherent supercontinuum laser is thus built with a broad bandwidth (780–1300 nm) and high spectral power (~1 mW/nm).

show abstract

Section: Methodsmentioning

confidence: 99%

Suppressing Short-Term Polarization Noise and Related Spectral Decoherence in All-Normal Dispersion Fiber Supercontinuum Generation

Liu

Zhao

Lyngsø

et al. 2015

J. Lightwave Technol.

Self Cite

View full text Add to dashboard Cite

show abstract

“…In contrast, low temporal coherence associated with large pulse-to-pulse fluctuations often plays a precision or resolution limiting role, for example in modalities using the coherence directly as content in the acquired signal, such as optical coherence tomography [5,6] or coherent antiStokes Raman scattering (CARS) spectroscopy [7]. Since spectral amplitude and phase fluctuations also translate into temporal jitter, ultrafast photonics applications usually demand SC sources with a high degree of coherence to enable, for example, beam synchronization and extraction of time-resolved information in multi-beam pump-probe techniques, nonlinear pulse compression, multimodal bio-photonic imaging, or coherent control experiments [8][9][10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Limits of coherent supercontinuum generation in normal dispersion fibers

et al. 2017

View full text Add to dashboard Cite

We study the largely unexplored transition between coherent and noise-seeded incoherent continuum generation in all-normal dispersion (ANDi) fibers and show that highly coherent supercontinua with spectral bandwidths of one octave can be generated with long pump pulses of up to 1.5 ps duration, corresponding to soliton orders of up to N = 600. In terms of N, this corresponds to an approximately 50 times increase of the coherent regime compared to anomalous dispersion pumping. In the transition region between coherent and incoherent spectral broadening we observe the manifestation of nonlinear phenomena that we term incoherent cloud formation and incoherent optical wave breaking, which lead to a gradual or instantaneous coherence collapse of SC spectral components, respectively. The role played by stimulated Raman scattering and parametric four-wave mixing during SC generation in ANDi fibers is shown to be more extensive than previously recognized: their nonlinear coupling contributes to the suppression of incoherent dynamics at short pump pulse durations, while it is responsible for non-phasematched parametric amplification of noise observed in the long pulse regime. We further discuss the dependence of SC coherence on fiber design, and present basic experimental verifications for our findings using single-shot detection of SC spectra generated by picosecond pulses. This work outlines both the further potential as well as the limitations of broadband coherent light source development for applications such as metrology, nonlinear imaging, and ultrafast photonics, amongst others.

show abstract

“…The femtoJock system implemented the multiphoton intrapulse interference phase scan (MIIPS) method [25, 26] that enabled the applied spectral phase for dispersion compensation and pulse compression of the fiber output to be found. Use of the femtoJock system [27] and similar pulse shapers for two photon microscopy has been reported previously [28]. …”

Section: Methodsmentioning

confidence: 99%

Dependence of Two-Photon eGFP Bleaching on Femtosecond Pulse Spectral Amplitude and Phase

et al. 2015

View full text Add to dashboard Cite

Photobleaching is a key limitation in two-photon imaging of fluorescent proteins with femtosecond pulsed excitation. We present measurements of the dependence of eGFP photobleaching on the spectral amplitude and phase of the pulses used. A strong dependence on the excitation wavelength was confirmed and measured over a 800–950 nm range. A fiber continuum light source and pulse shaping techniques were used to investigate photobleaching with broadband, 15 fs transform limited, pulses with differing spectral amplitude and phase. Narrow band pulses, >150 fs transform limited, typical of femtosecond laser sources used in two-photon imaging applications, were also investigated for their photobleaching dependence on pulse dispersion and bandwidth. The bleach rate for broadband pulses was found to be primarily determined by the second harmonic spectrum of the excitation light. On the other hand, for narrow band excitation pulses with similar center wavelengths improvement in bleach rate was found to be mostly dependent on reducing the pulse length. A simple model to predict the relative bleach rates for broadband pulses is presented and compared to the experimental data.

show abstract

Multimodal Nonlinear Microscopy by Shaping a Fiber Supercontinuum From 900 to 1160 nm

Cited by 36 publications

References 43 publications

Suppressing Short-Term Polarization Noise and Related Spectral Decoherence in All-Normal Dispersion Fiber Supercontinuum Generation

Suppressing Short-Term Polarization Noise and Related Spectral Decoherence in All-Normal Dispersion Fiber Supercontinuum Generation

Limits of coherent supercontinuum generation in normal dispersion fibers

Dependence of Two-Photon eGFP Bleaching on Femtosecond Pulse Spectral Amplitude and Phase

Contact Info

Product

Resources

About