2017
DOI: 10.21037/jtd.2017.06.99
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Multimodality imaging assessment of mitral valve anatomy in planning for mitral valve repair in secondary mitral regurgitation

Abstract: Secondary mitral regurgitation (MR) is frequent valvular heart disease and conveys worse prognostic. Therapeutic surgical or percutaneous options are available in the context of severe symptomatic secondary MR, but the best approach to treat these patients remains unclear, given the lack of clear clinical evidence of benefit. A comprehensive evaluation of the mitral valve apparatus and the left ventricle (LV) has the ability to clearly define and characterize the disease, and thus determine the best option for… Show more

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Cited by 16 publications
(5 citation statements)
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“…The MR jet is central in patients with global wall motion abnormalities, with equal lateral displacement of the PMs, similar to nonischemic cardiomyopathy 21 (Figure 3 might occur in patients with multiple vessel disease and old inferior MI, mainly affecting the posterior PM. 21 The jet is posterior in patients with dominant posterior leaflet tethering 22 (Figure 3(c), (d)). MA enlargement and flattening with increased leaflet stress is another factor contributing to the development of FMR.…”
Section: Complex Anatomy Of the MVmentioning
confidence: 98%
“…The MR jet is central in patients with global wall motion abnormalities, with equal lateral displacement of the PMs, similar to nonischemic cardiomyopathy 21 (Figure 3 might occur in patients with multiple vessel disease and old inferior MI, mainly affecting the posterior PM. 21 The jet is posterior in patients with dominant posterior leaflet tethering 22 (Figure 3(c), (d)). MA enlargement and flattening with increased leaflet stress is another factor contributing to the development of FMR.…”
Section: Complex Anatomy Of the MVmentioning
confidence: 98%
“…Regarding MR, as mentioned, echocardiography is crucial in determining etiology, morphology, and mechanism, especially in secondary or functional origin cases. Therefore, many echocardiographic methods should be considered to quantify MR [27,[49][50][51][52], as reported in Table 2. The 2020 American College of Cardiology/American Heart Association Guidelines report that threshold criteria for functional MR should now be similar to that for primary MR, i.e., effective regurgitant orifice area (EROA) ≥ 0.4 cm 2 , regurgitant volume (RVol) ≥ 60 mL, and a regurgitant fraction (RF) ≥ 50% [53].…”
Section: Resting Echocardiographymentioning
confidence: 99%
“…In addition, it helps understand the etiology of the underlying pathological process, especially in secondary MR. Moreover, CMR provides better spatial resolution, which aids in the detailed characterization of MV morphology and subvalvular apparatus [49]. It also quantifies MV RVol (MRV) using direct methods based on the velocity-encoded sequences and indirect quantifications based on the various SV calculations using the volumetric method or PC imaging [106].…”
Section: Cmr Is the Most Useful Imaging Technique For Differentiating...mentioning
confidence: 99%
“…The MV tenting area and tethering pattern reflect the severity of adverse MV apparatus remodeling and the extent of papillary muscle displacement. An increased MV tenting area represents apical tethering of the MV leaflets and movement of the coaptation point away from the annulus [26]. These alterations increase in severity with more global or extensive LV remodeling, such as after a large anterior wall MI or severe multivessel coronary artery disease [3,27].…”
Section: Commentmentioning
confidence: 99%