Multimodality Imaging: Coronary Calcium Scoring And Myocardial Blood Flow Reserve To Predict Underlying Multivessel Coronary Artery Disease

Lehenbauer, Kyle; Qarajeh, Raed; Shatla, Islam; Singh, Annapoorna; Patel, Krishna; Peri-Okonny, Poghni; Kennedy, Kevin F.; Torres, Nohora X.; Myadam, Rahul; Sperry, Brett W.; Saeed, Ibrahim M.; Thompson, Randall C.; McGhie, A. Iain; Bateman, Timothy M.

doi:10.1016/j.jcct.2020.06.121

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Table 1: Laboratory Values On the Day Of Admission1

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2023

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“…Her preceding pulmonary symptoms and weight loss, mucocutaneous ulcerations, with a subsequent note of Histoplasma capsulatum (H. capsulatum) on bone marrow biopsy, suggested DH was the likely etiology of this subacute presentation. The differential diagnosis for this patient is broad, including infectious, noninfectious, and cardiac causes [4][5][6][7][8][9][10][11][12][13][14][15].…”

Section: Table 1: Laboratory Values On the Day Of Admissionmentioning

confidence: 99%

An Interesting Case of Disseminated Histoplasmosis in a Patient With Hemophagocytic Lymphohistiocytosis

Pellegrino¹,

Naik²,

Bali³

2023

Cureus

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Histoplasmosis is a common mycosis in North and Central America caused by Histoplasma capsulatum. Affected patients typically remain asymptomatic. However, in some individuals, histoplasmosis can present as a severe illness, usually occurring in patients with underlying risk factors such as the immunocompromised (e.g., acquired immunodeficiency syndrome (AIDS), treatment with immunosuppressive agents), and the elderly without underlying immunocompromised conditions. Here, we present a case of disseminated histoplasmosis diagnosed as an incidental finding on bone marrow biopsy while treating a hospitalized patient for hemophagocytic lymphohistiocytosis. The patient presented with weight loss, anorexia, fatigue, and generalized weakness. The patient was successfully treated with amphotericin B and eventually transitioned to itraconazole.

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