Multimodality treatment planning using the Markov decision process: a comprehensive study of applications and challenges

Singh, Pushpendra; Singh, Seema; Mishra, Alka; Mishra, Santosh Kumar

doi:10.1007/s42600-024-00349-4

Res. Biomed. Eng.

2024

DOI: 10.1007/s42600-024-00349-4

|View full text |Cite

Multimodality treatment planning using the Markov decision process: a comprehensive study of applications and challenges

Pushpendra Singh,

Seema Singh,

Alka Mishra

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 79 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

An Optimal Framework for the Effective Delivery of the Radiation to the target by Considering the Case of Head and Neck Cancer

Singh,

Dewangan,

Potdar

et al. 2024

Polish Journal of Medical Physics and Engineering

View full text Add to dashboard Cite

Introduction: Delivering the required dose to the intended target while limiting the radiation’s impact on adjacent normal tissue is the principal goal of radiotherapy. One effective method for doing this is intensity-modulated radiotherapy, which operates on the idea of inverse planning. In order to transmit the fluence to the target efficiently while sparing the healthy cells, the objective of the research is to generate the ideal radiation dosage by first optimizing the fluence and then adjusting the trajectory of the leaf. Materials and Methods: Fluence mapping is utilized in inverse planning to calculate each beam’s intensity level. Considering dose-volume limitations on the OARs, five evenly spaced beams expose the intended target for examination. The efficacy of the therapy regimens was measured using cumulative DVH. We have taken into account a number of PTVs and OARs acquired from the CORT dataset, which is accessible publicly for the benefit of researchers, to validate our approach. Results: For the various target area and critical organs, we fixed the radiation levels at 82 Gy and 61 Gy across the PTV-70 and PTV-56, and similarly, the dose volumes of 52 Gy, 40 Gy, and 32 Gy across the Spinal Cord, Spinal Cord PRV, and Left and Right Parotid. Analysis of the data indicates that our approach generates the highest D95 dosage level possible across the target area for each PTV. Additionally, relative to other approaches employed in the literature, our approach’s duration for analysis (254.28 Seconds) is extremely low. Conclusion: The suggested approach can produce global minima for IMRT planning with consistent quality across a range of treatment plans and effectively improve safety for substantial dual OARs.

show abstract

An Optimal Framework for the Effective Delivery of the Radiation to the target by Considering the Case of Head and Neck Cancer

Singh,

Dewangan,

Potdar

et al. 2024

Polish Journal of Medical Physics and Engineering

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Multimodality treatment planning using the Markov decision process: a comprehensive study of applications and challenges

Cited by 1 publication

References 79 publications

An Optimal Framework for the Effective Delivery of the Radiation to the target by Considering the Case of Head and Neck Cancer

An Optimal Framework for the Effective Delivery of the Radiation to the target by Considering the Case of Head and Neck Cancer

Contact Info

Product

Resources

About