Multimorbidity and quality of life: a closer look

Fortin, Martin; Dubois, Marie‐France; Hudon, Catherine; Soubhi, Hassan; Almirall, José

doi:10.1186/1477-7525-5-52

Cited by 238 publications

(243 citation statements)

References 23 publications

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“…It has been validated for use with primary care patients (24), converges with coroner’s pathology reports (25), and is a strong predictor of health-related quality of life (26) and survival (27–29). The CIRS quantifies the level of overall medical burden through ratings of disease severity (0 = no burden, 1 = mild burden, 2 = moderate burden, 3 = major burden, 4 = severe burden) across the following major organ systems: Cardiovascular/Respiratory (combining cardiac, vascular, upper respiratory, and Eyes Ears Nose and Throat items), Genitourinary, Musculoskeletal, Neurological, Gastrointestinal (combining upper and lower gastrointestinal and hepatic items), and Endocrine/Metabolic.…”

Section: Methodsmentioning

confidence: 99%

Personality and Physician-Assessed Illness Burden in Older Primary Care Patients Over 4 Years

Chapman

Roberts

Lyness

et al. 2013

The American Journal of Geriatric Psychiatry

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Background Personality traits have been associated with physician-rated illness burden cross-sectionally, but longitudinal associations between personality and objective medical morbidity remain unclear. Purpose To examine associations between personality and physician-rated illness burden 4 years prospectively in older primary care patients. Method At baseline, patients (average age = 75, SD = 6.6, 62% female) completed the NEO-Five Factor Inventory. At baseline and 4 yearly follow-ups, a physician completed the Cumulative Illness Rating Scale based on medical records. Results Linear mixed effects models revealed that higher neuroticism and lower conscientiousness predicted worse average illness burden longitudinally. Relatively disagreeable persons (25th percentile) accumulated morbidity at a 33% faster rate than agreeable (75th percentile) peers. At the final follow-up, a person at the 75th percentile of neuroticism and the 25th percentile of conscientiousness and agreeableness showed morbidity comparable to a peer of average personality but 10 years older. An individual at the 25th percentile of neuroticism and 75th percentile of conscientiousness and agreeableness showed end-point illness burden comparable to a peer of average personality but 10 years younger. 21% of the morbidity associated with neuroticism was explained by total cholesterol. History of hypertension, smoking, alcohol/drug abuse, and affective symptoms of depression each explained 10% or less of the other observed personality effects. Conclusion Personality plays a non-trivial role in healthy aging among older persons. Brief personality assessment may identify at-risk older persons for closer monitoring, enhance the accuracy of medical prognosis, and provide clues for clinical interventions to promote better health.

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Section: Methodsmentioning

confidence: 99%

Personality and Physician-Assessed Illness Burden in Older Primary Care Patients Over 4 Years

Chapman

Roberts

Lyness

et al. 2013

The American Journal of Geriatric Psychiatry

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“…Comorbidity increases the complexity of patient management, often leading to poorer health outcomes and increased health care costs 15, 16. Comorbidity also poses a huge financial and health burden on households, especially in sub‐Saharan Africa where poverty levels are high with rising cost for healthcare utilization 1, 5, 10.…”

Section: Introductionmentioning

confidence: 99%

High prevalence of HIV and non‐communicable disease (NCD) risk factors in rural KwaZulu‐Natal, South Africa

et al. 2017

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IntroductionSouth Africa faces epidemics of HIV and non‐communicable diseases (NCDs). The aim of this study was to characterize the prevalence of non‐communicable disease risk factors and depression, stratified by HIV status, in a community with a high burden of HIV.MethodsWe conducted a home‐based HIV counselling and testing study in KwaZulu‐Natal, South Africa between November 2011 and June 2012. Contiguous households were approached and all adults ≥18 years old were offered an HIV test. During follow‐up visits in January 2015, screening for HIV, depression, obesity, blood glucose, cholesterol and blood pressure were conducted using point‐of‐care tests.ResultsOf the 570 participants located and screened; 69% were female and 33% were HIV‐positive. NCD risk factor prevalence was high in this sample; 71% were overweight (body mass index (BMI) 25 to 29.9 kg/m2) or obese (BMI≥30 kg/m2), 4% had hyperglycaemia (plasma glucose >11.0 mmol/l/200 mg/dl), 33% had hypertension (HTN, >140/90 mmHg), 20% had hyperlipidaemia (low density cholesterol >5.2 mmol/l/193.6 mg/dl) and 12% had major depressive symptoms (nine item Patient Health Questionnaire ≥10). Of the 570 participants, 87% had one or more of HIV, hyperglycaemia, HTN, hyperlipidaemia and/or depression. Over half (56%) had two or more. Older age and female gender were significantly associated with the prevalence of both HIV infection and NCD risk factors. Around 80% of both HIV‐positive and negative persons had one of the measured risk factors (i.e. obesity, hyperglycaemia, hyperlipidaemia, HTN), or depression.ConclusionsIn a community‐based sample of adults in KwaZulu‐Natal, South Africa, the prevalence of both HIV infection and NCD risk factors were high. This study is among the first to quantify the substantial burden of NCD risk factors and depression in this non‐clinic based population.

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“…Er illustrierte dies zunächst am Beispiel des Diabetes mellitus [11]. Ein Einfluss von Komorbidität auf die Mortalität und verschiedene andere Krankheitsendpunkte ist seither bei Personen mit unterschiedlichen Erkrankungen vielfach nachgewiesen worden [3,8,12]. Anders als bei der Komorbidität wird bei der Multimorbidität keine bestimmte Erkrankung vorrangig betrachtet [7].…”

Section: Multimorbidität -Konzept Und Gesundheitspolitische Bedeutungunclassified

“…Auch wenn bislang kein wissenschaftlicher Konsens erzielt werden konnte, besteht kein Zweifel daran, dass das gleichzeitige Vorliegen mehrerer Gesundheitsprobleme von hoher sozialmedizinischer und gesundheitsökonomischer Bedeutung ist. Dies gilt vor allem für chronische Erkrankungen, die eine dauerhafte oder wiederkehrende medizinische Behandlung erfordern [12,13,14]. …”

Section: Multimorbidität -Konzept Und Gesundheitspolitische Bedeutungunclassified

Herausforderungen an die Gesundheitsforschung für eine alternde Gesellschaft am Beispiel „Multimorbidität“

Scheidt‐Nave

Richter

Fuchs

et al. 2010

Bundesgesundheitsbl.

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Multimorbidity and quality of life: a closer look

Cited by 238 publications

References 23 publications

Personality and Physician-Assessed Illness Burden in Older Primary Care Patients Over 4 Years

Personality and Physician-Assessed Illness Burden in Older Primary Care Patients Over 4 Years

High prevalence of HIV and non‐communicable disease (NCD) risk factors in rural KwaZulu‐Natal, South Africa

Herausforderungen an die Gesundheitsforschung für eine alternde Gesellschaft am Beispiel „Multimorbidität“

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