Multimorbidity in primary care: Prevalence and trend over the last 20 years

Uijen, Annemarie; Lisdonk, E.H. van de

doi:10.1080/13814780802436093

Cited by 420 publications

(389 citation statements)

References 9 publications

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“…The results remained when adjusting for age and sex meaning that compositional changes in the samples did not explain the observed time trend. Yet, consistent with previous studies that investigated factors associated to health (Agborsangaya et al 2012;Uijen and van de Lisdonk 2008), our results indicated that female sex, higher age, and low education significantly and independently increased the odds of having complex health problems. If the level of education had not increased as it did between 1992 and 2011, the increase in complex health problems would probably have been greater.…”

Section: Discussionsupporting

confidence: 82%

Complex health problems among the oldest old in Sweden: increased prevalence rates between 1992 and 2002 and stable rates thereafter

et al. 2015

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Studies of health trends in older populations usually focus on single health indicators. We include multiple medical and functional indicators, which together indicate the broader impact of health problems experienced by individuals and the need for integrated care from several providers of medical and long-term care. The study identified severe problems in three health domains (diseases/ symptoms, mobility, and cognition/communication)

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Section: Discussionsupporting

confidence: 82%

Complex health problems among the oldest old in Sweden: increased prevalence rates between 1992 and 2002 and stable rates thereafter

et al. 2015

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“…Uijen and van de Lisdonk described a doubling prevalence of chronic diseases in the patient files of 10 general practitioners in 1985-2005. 23 Also, the percentage of patients with at least four chronic diseases increased with approximately 300%. Tacken et al reported that the prevalence of chronic pulmonary disease, cardiac disease or diabetes mellitus among patients over 65 years attending a general practitioner increased from 41.8% to 46.8% in 6 years (2003)(2004)(2005)(2006)(2007)(2008)(2009)).…”

Section: Discussionmentioning

confidence: 99%

Increasing prevalence of comorbidity in patients with colorectal cancer in the South of the Netherlands 1995–2010

Leersum

Janssen‐Heijnen

Wouters

et al. 2012

Intl Journal of Cancer

103

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Comorbidity has large impact on colorectal cancer (CRC) treatment and outcomes and may increase as the population ages. We aimed to evaluate the prevalence and time trends of comorbid diseases in patients with CRC from 1995 to 2010. The Eindhoven Cancer Registry registers comorbidity in all patients with primary CRC in the South of the Netherlands. We analyzed the prevalence of serious comorbid diseases in four time frames from 1995 to 2010. Thereby, we addressed its association with age, gender and socio-economic status (SES). The prevalence of comorbidity was registered in 27,339 patients with primary CRC. During the study period, the prevalence of comorbidity increased from 47% to 62%, multimorbidity increased from 20% to 37%. Hypertension and cardiovascular diseases were most prevalent and increased largely over time (respectively 16-29% and 12-24%). Pulmonary diseases increased in women, but remained stable in men. Average age at diagnosis increased from 68.3 to 69.5 years (p 5 0.004). A low SES and male gender were associated with a higher risk of comorbidity (not changing over time). This study indicates that comorbidity among patients with CRC is common, especially in males and patients with a low SES. The prevalence of comorbidity increased from 1995 to 2010, in particular in presumably nutritional diseases. Ageing, increased life expectancy and life style changes may contribute to more comorbid diseases. Also, improved awareness among health care providers on the importance of comorbidity may have resulted in better registration. The increasing burden of comorbidity in patients with CRC emphasizes the need for more focus on individualized medicine.Comorbidity composes a great challenge when treating patients with colorectal cancer (CRC). [1][2][3][4] In the Netherlands, CRC represents the second most frequent cancer in terms of incidence with more than 12,000 newly diagnosed patients annually and a lifetime risk of more than 5%. 5 As more than half of patients with CRC is aged older than 70 years, the diagnosis of CRC is often made amidst the presence of other chronic medical conditions. Treatment of patients with severe comorbidity is challenging because of polypharmacy and decreased compensating mechanisms, especially in older patients who also have normal age-related physiological changes. 6 The presence of a single or combination of chronic illnesses can affect both treatment effectiveness and tolerance, and is associated with worse short-and long-term outcomes after CRC surgery. [1][2][3][4][7][8][9][10][11] The prevalence of comorbidity is influenced by personal and environmental factors. Age, gender and socio-economic status (SES) have been described as interacting with the burden of specific comorbid ailments and influencing outcomes after CRC treatment. [12][13][14] Further, ageing, improved life expectancy and lifestyle habits in western countries will lead to a higher prevalence of (multiple) concomitant diseases among patients with CRC. 15,16 Objectifying increases in the burden of comorbi...

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“…The high prevalence of multimorbidity is predominantly attributed to the growing incidence of chronic conditions (2), coupled with the increasing life-expectancy, and it is without a doubt one of the most significant challenges faced by health care providers and policymakers (3,4). Multimorbidity is associated with increased use of health care services (5), a lower quality of life (6), and a higher risk for premature mortality (7).…”

mentioning

confidence: 99%

Perceived Stress and Its Relationship With Chronic Medical Conditions and Multimorbidity Among 229,293 Community-Dwelling Adults in 44 Low- and Middle-Income Countries

Vancampfort¹,

Koyanagi²,

Ward³

et al. 2017

American Journal of Epidemiology

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This study assessed the association of chronic conditions and multimorbidity with perceived stress among community-dwelling adults in 44 low-and middle-income countries. Data were analyzed from the World Health Survey (2002)(2003)(2004) (18.29, 22.05) respectively. The associations with perceived stress were significantly stronger among the poorest for arthritis, asthma, diabetes, edentulism, and ≥4 chronic conditions. Our data suggest that a range of chronic conditions and multimorbidity are associated with greatly increased perceived stress among people in low-and middle-income countries, and that the poorest may be a particularly vulnerable group.

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Multimorbidity in primary care: Prevalence and trend over the last 20 years

Cited by 420 publications

References 9 publications

Complex health problems among the oldest old in Sweden: increased prevalence rates between 1992 and 2002 and stable rates thereafter

Complex health problems among the oldest old in Sweden: increased prevalence rates between 1992 and 2002 and stable rates thereafter

Increasing prevalence of comorbidity in patients with colorectal cancer in the South of the Netherlands 1995–2010

Perceived Stress and Its Relationship With Chronic Medical Conditions and Multimorbidity Among 229,293 Community-Dwelling Adults in 44 Low- and Middle-Income Countries

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