Multiparametric chemical exchange saturation transfer MRI detects metabolic changes in mild cognitive impairment cases at 3.0 Tesla.
Dongyong Zhu,
Xiaona Fu,
Jia Liu
et al.
Abstract:This study aimed to assess the potential of multiparametric chemical exchange saturation transfer magnetic resonance imaging (CEST MRI) for MCI detection. Twenty-eight patients with MCI and 31 age- and gender-matched normal controls (NCs) were enrolled. CEST MRI was performed with a gradient and spin-echo sequence on a 3T scanner. Multi-parametric CEST parameters were analyzed, such as amide, amine, amine and amide concentration independent assay (AACID), magnetization transfer ratio yielding rex (MTRrex-amide… Show more
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