Multiparametric Quantitative MRI of Peripheral Nerves to Differentiate Axonal from Demyelinating Neuropathies (P11-8.002)

Response to “Validity of Quantitative, Multi‐Parametric MRI in the Diagnosis of Polyneuropathies”

“…However, it is still important to differentiate primary demyelinating polyneuropathies from axonal polyneuropathies in clinical care, as the two types of diseases respond to treatments differently. The preliminary study did show different patterns of qMRI values in demyelinating patients compared to axonal patients, 6 though these preliminary data should be further investigated in a larger cohort of patients to determine its added value in differentiating axonal from demyelinating polyneuropathies. In terms of differentiating nerve fiber types, we agree that MRI is largely nonspecific due to the limited imaging spatial resolution.…”