The topic of research included in this article was the evaluation of the influence of cenospheres on selected parameters of mortar cement. Samples were designed as CEM I 42.5 R Portland cement with the application of different additive amounts. In the experimental work, the consistency, compressive strength, and bending strength were tested after 28 and 56 days of maturation, and after heating temperatures of 20, 300, 500, and 700 °C. The compressive strength was tested on half beams (40 × 40 × 160 mm). Using the obtained results, the properties of the mortars were compared. The research confirmed the possibility of producing cenosphere-modified cement mortars. Cenospheres used in the preparation of cement mortar negatively affected the bending and compressive strength with increasing temperature (20, 300, 500, 700 °C) and increasing content of this additive (10, 20, 30%).