Orthogonal Frequency Division Multiplexing (OFDM) and Multicarrier Code DivisionMultiple Access (MC-CDMA) systems are comparatively evaluated for Power Line Communications (PLC) in a frequency-selective fading environment with additive colored Gaussian noise which is used to model the actual in-home powerline channel. OFDM serves as a benchmark in order to measure the performance of various MC-CDMA systems, since multicarrier modulation systems are considered the best candidate for this kind of channel. Both single-user and multi-user cases are taken into account, making use of the appropriate combiner schemes to take full advantage of each case.System efficiency is enhanced by the application of different coding techniques, a fact which shows that powerful coding can make the difference under such a hostile