2016
DOI: 10.1155/2016/7040352
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Multiple Brain Abscesses due toStreptococcus anginosus: Prediction of Mortality by an Imaging Severity Index Score

Abstract: An elderly patient with altered mental status, brain abscesses, ventriculitis, and empyemas died of septic shock and brain abscesses secondary to Streptococcus anginosus despite aggressive treatment. An imaging severity index score with a better prognostic value than the Glasgow coma scale predicted mortality in this patient.

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Cited by 8 publications
(4 citation statements)
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“…There is no gold standard for the identification of SAG. Cultivation methods and the available biochemical test are not sufficient for precise identification of the species, therefore it is necessary to use molecular techniques ( Wenzler et al, 2015 ; Kragha, 2016 ). Among them, two 16S rRNA real-time PCR assays were developed.…”
Section: Identification Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…There is no gold standard for the identification of SAG. Cultivation methods and the available biochemical test are not sufficient for precise identification of the species, therefore it is necessary to use molecular techniques ( Wenzler et al, 2015 ; Kragha, 2016 ). Among them, two 16S rRNA real-time PCR assays were developed.…”
Section: Identification Methodsmentioning
confidence: 99%
“…As described above, head and neck infections are caused by SAG, however, the routes of bacterial spread are poorly explored ( OPEN QUESTION 3 ). Among the routes considered for brain infection are contiguous infection, hematogenous spread, direct implant, trauma or neurosurgery, and peripheral nerves ( Kragha, 2016 ).…”
Section: Streptococcus Anginosus Group – Opportunistic Patho...mentioning
confidence: 99%
“…Cerebritis may occur for hematogenous spread, direct posterior sinonasal spread, perineural spread, after trauma or as neurosurgical complication; however, from 15% to 30% of brain infections are classified as cryptogenic if the source cannot be found [ [36] , [37] , [38] , [39] ]. Cerebritis presents as an indistinct region of acute inflammation in the brain tissue characterized by enhanced blood vessel permeability in the absence of neo-angiogenesis [ 40 , 41 ].…”
Section: Discussionmentioning
confidence: 99%
“…S. constellatus is an uncommon cause of soft tissue abscesses and a rare cause of brain abscesses. However, immunosuppressed states increase the risk of developing invasive pyogenic infections due to S. constellatus [ 7 , 8 ].…”
Section: Discussionmentioning
confidence: 99%