Multiple clustered dermatofibromas (fibrous histiocytomas): an atypical clinical variant of dermatofibroma

Shaheen, Babar; Saldanha, Gerald; Calonje, Eduardo; Johnston, Graham A.R.

doi:10.1111/ced.12200

Cited by 16 publications

(23 citation statements)

References 7 publications

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“…The clinical characteristics of this case shows all the features common to all cases of this variant form of DF previously reported, these being, occurrence in healthy individual in the second decade, slowly progressive evolution increasing over many years [9,10] and DF typical lesions. The location on the left buttock is also quite typical, and 2 biopsies on different places were consistent with dermatofibroma [11,12] . In our case the patient was asymptomatic, with pericardial cyst accidentally identified.…”

Section: Discussionmentioning

confidence: 83%

Multiple clustered dermatofibroma associated with asymptomatic pericardial cyst

Brzeziński

Kazlouskaya

Bimbi³

2017

J Surg Dermatol

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Multiple clustered dermatofibroma (MCDF) is an unusual variant of dermatofibroma (DF) presentation, localized on one segment of the body. Multiple dermatofibroma is a term for when there are more than 15 dermatofibromas, which in itself is already a rare condition. The dermatofibromas usually appear in younger adults and are predominantly located on lower parts of the body. No associations, except one case with pulmonary hypertension, were described in patients with MCDF. Herein we present another case of this rare complaint in a 58 year old female with clustered lesions on the thigh. Pericardial cyst was identified in our patient during routine chest X-ray and the patient is asymptomatic. MCDFs do not usually require treatment unless requested by the patient for cosmetic reason. This variant of MCDF, which is neither congenital nor eruptive, is extraordinarily rare, with only 13 cases reported. Further reports may identify possible associations of MCDF.Keywords: Dermatofibroma; histiocytomas; pericardial cyst Citation: Brzezinski P, Kazlouskaya V, Bimbi C. Multiple clustered dermatofibroma associated with asymptomatic pericardial cyst.

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Section: Discussionmentioning

confidence: 83%

Multiple clustered dermatofibroma associated with asymptomatic pericardial cyst

Brzeziński

Kazlouskaya

Bimbi³

2017

J Surg Dermatol

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“…5 Multipl kümelenmiş dermatofibrom tek bir anatomik bölgede gruplaşmış dermatofibrom lezyonlarını tanımlamakta olup, bu tanı ile sınırlı sayıda olgu bildirilmiştir. 6,7 Uzun yıllar süren seyir sonunda bazı olgularda kendi kendine gerileme görülebilmektedir. 3 Soliter ve az sayıdaki dermatofibromlar sistemik hastalık açısından önem taşımaz.…”

Section: Discussionunclassified

“…[22][23][24][25][26][27][28] Tablo 1'de literatürde 18 yaş ve altında bildirilen multipl dermatofibrom olguları görül-mektedir. 4,6,[29][30][31] Literatür taranarak elde edilen 18 yaş altı MED tanılı olgular incelendiğinde cinsiyet açısın-dan fark saptanmamış olup, olguların hiçbirinde eşlik eden hastalık veya sistemik tedavi kullanımı bildirilmemiştir. Lokalizasyonun ağırlıklı olarak gövde ve ekstremite dağılımlı olduğu gözlen-miştir.…”

Section: Discussionunclassified

A Case of Idiopathic Dermatofibromatosis

Mullaaziz¹,

Özkayalar²,

Kaptanoğlu³

et al. 2015

Turkiye Klinikleri J Dermatol

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“…Techniques used with varying success include cryotherapy, intralesional steroids, surgery and phototherapy. 13,14 radiography of the thorax also indicated no anomalies. With the patient's consent, the decision was made to continue ustekinumab treatment.…”

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confidence: 89%

“…12 Clinically, the lesions may mimic atypical fibroxanthomas, nodular fasciitis and dermatofibrosis lenticularis disseminata. 13 From a therapeutic point of view, a conservative approach is advisable. Techniques used with varying success include cryotherapy, intralesional steroids, surgery and phototherapy.…”

mentioning

confidence: 99%