Multiple Emulsion Stability: Pressure Balance and Interfacial Film Strength

Jiao, Jim; Burgess, Diane J.

doi:10.1002/9780470209264.ch1

Cited by 17 publications

(28 citation statements)

References 24 publications

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“…16 On the other hand, it causes swelling and possibly rupturing of the inner aqueous droplets because of water influx resulting from increased internal osmotic pressure. Table 3 shows the stability of W/O/W multiple emulsions containing sodium salicylate or sodium chloride in either the internal or the external aqueous phases 1 year following preparation as previously 17 reported. Formulations 3 and 14, with 0% or 0.5% wt/vol sodium salicylate in the internal aqueous phase and no salt in the external aqueous phase, which had a moderate viscosity initially, showed good stability.…”

Section: Rheological Properties Of W/o/w Multiple Emulsions At Differmentioning

confidence: 99%

Rheology and stability of water-in-oil-in-water multiple emulsions containing Span 83 and Tween 80

2003

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KEYWORDSmultiple emulsions, stability, rheology, surfactant Multiple emulsions are often stabilized using a combination of hydrophilic and hydrophobic surfactants. The ratio of these surfactants is important in achieving stable multiple emulsions. The objective of this study was to evaluate the long-term stability of water-in-oil-in-water (W/O/W) multiple emulsions with respect to the concentrations of Span 83 and Tween 80. In addition, the effect of surfactant and electrolyte concentration on emulsion bulk rheological properties was investigated. Light microscopy, creaming volume, and rheological properties were used to assess emulsion stability. It was observed that the optimal surfactant concentrations for W/O/W emulsion long-term stability were 20% wt/vol Span 83 in the oil phase and 0.1% wt/vol Tween 80 in the continuous phase. Higher concentrations of Tween 80 had a destructive effect on W/O/W emulsion stability, which correlated with the observation that interfacial film strength at the oil/water interface decreased as the Tween 80 concentration increased. High Span 83 concentrations increased the storage modulus Gƍ (solidlike) values and hence enhanced multiple emulsion stability. However, when 30% wt/vol Span 83 was incorporated, the viscosity of the primary W/O emulsion increased considerably and the emulsion droplets lost their shape. Salt added to the inner aqueous phase exerted an osmotic pressure that caused diffusion of water into the inner aqueous phase and increased W/O/W emulsion viscosity through an increase in the volume fraction of the primary W/O emulsion. This type of viscosity increase imposed a destabilizing effect because of the likelihood of rupture of the inner and multiple droplets.

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Section: Rheological Properties Of W/o/w Multiple Emulsions At Differmentioning

confidence: 99%

Rheology and stability of water-in-oil-in-water multiple emulsions containing Span 83 and Tween 80

2003

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“…36,37 However, the fact that DEs are thermodynamically unstable has limited their applications, especially so in the pharmaceutical industry. 38 This instability problem can be overcome by selecting an oil phase, which upon freezing preserves the mechanical stability of the oil globule and its contents, thus preventing mass transport between phases. Subsequent thawing triggers coalescence of the droplets of W 1 with W 2 phase, 39,40 termed external coalescence.…”

Section: Introductionmentioning

confidence: 99%

Oil-Frozen W1/O/W2 Double Emulsions for Dermal Biomacromolecular Delivery Containing Ethanol as Chemical Penetration Enhancer

Jaimes-Lizcano

Lawson

Papadopoulos

2011

Journal of Pharmaceutical Sciences

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“…As concentrated and diluted JEs showed better kinetic stability, this emphasis the idea of lowering the interfacial tension between used oils by encapsulating them in one globule next to each other (31). As low HLB and high HLB surfactants were used in concentrated and diluted DE, this supposed to enhance particles' stability but emulsions tend to separate after 3 min of their formation, which proves that using two surfactants in the emulsion can partially enhance kinetic stability, but emulsions' topologies play a significant role in their kinetic stability.…”

Section: Emulsion Preparation and Observationmentioning

confidence: 99%

Fungicidal and nematicidal activities for essential oils formulated in Janus emulsion

Sharar

Bozeya

Al-Banna

et al. 2017

Green Chemistry Letters and Reviews

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This study investigated the nematicidal and fungicidal activities of the two immiscible camphor and orange oils formulated in Janus emulsion (JE). JE was prepared from camphor and orange oils by a single-step emulsification with different concentrations chosen from an established phase diagram. Camphor oil nematicidal activity was studied against the root knot nematode Meloidogyne incognita, while orange oil fungicidal activity was studied against the wilt fungus Fusarium oxysporum f. sp. lycopersici (Fol). For a comparison study, different concentrations of JE and double emulsions were prepared. Results showed that JE had a significant mortality effect on the secondstage juveniles (J2s) M. incognita with 81% mortality and was able to delay the growth of Fol four and seven days after exposure, while changes in the efficiency of DE were recorded. Prepared JEs were shown to maintain the efficiency and to have slow release profiles for encapsulated oils.ARTICLE HISTORY

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Multiple Emulsion Stability: Pressure Balance and Interfacial Film Strength

Cited by 17 publications

References 24 publications

Rheology and stability of water-in-oil-in-water multiple emulsions containing Span 83 and Tween 80

Rheology and stability of water-in-oil-in-water multiple emulsions containing Span 83 and Tween 80

Oil-Frozen W1/O/W2 Double Emulsions for Dermal Biomacromolecular Delivery Containing Ethanol as Chemical Penetration Enhancer

Fungicidal and nematicidal activities for essential oils formulated in Janus emulsion

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