Multiple endokrine Neoplasie

Schaaf, Ludwig; Raue, Friedhelm

doi:10.1055/a-1023-5221

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2024

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“…MEN1 is characterized by the combined occurrence of parathyroid, pituitary and pancreatic neuroendocrine tumors, whereas MEN2 features medullary thyroid cancer in association with phaeochromocytoma and parathyroid tumors. Although both MEN1 and MEN2 are autosomal dominant disorders, they have contrasting molecular etiologies: MEN1 results from inactivating germline mutations of the MEN1 tumor suppressor gene on chromosome 11 (14), whereas MEN2 results from activating mutations in the RET proto-oncogene. Fully understanding if patients have hyperparathyroidism or MEN family history aids in the early diagnosis or treatment of APA.…”

Section: Figurementioning

confidence: 99%

Case report: Ultrasound misdiagnoses atypical parathyroid adenoma as malignant thyroid tumor

Hou,

Zhao,

Sun

et al. 2024

Front. Oncol.

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Atypical Parathyroid Adenoma (APA) is a type of tumor that lies somewhere between parathyroid adenoma and parathyroid carcinoma. It often affects adults over the age of 60, and the clinical symptoms are consistent with those of hyperparathyroidism. This condition has a low occurrence, and its ultrasonographic signs are strikingly similar to thyroid malignant tumors, making it easily misdiagnosed. As a result, a case of APA ultrasonography misdiagnosis admitted to our hospital was recorded in order to serve as a reference point for APA diagnosis.

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Section: Figurementioning

confidence: 99%