Multiple eruptive benign keratoses associated with cyclosporine therapy for psoriasis

Multiple Dermatofibromas Accompanied by Eruptive Benign Keratoses in a Patient with Systemic Lupus Erythematosus

“…MUltiple eruptive BK were previously described in patients with psoriasis undergoing cyclosporine A therapy. They showed numerous verrucous nodular lesions, and their histology revealed hyperkeratosis and acanthosis (13,14). While it may be coincidental, altered immunity may have played a role in the pathogenesis of these two conditions in the present case.…”

“…Previously, several authors have described cases of multiple DFs associated with autoimmune disorder, altered immunity, or both (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). In contrast, eruptive benign keratoses (BK) are described in patients with psoriasis undergoing cyclosporin A therapy (13,14). We describe here a woman with systemic lupus erythematosus (SLE) in whom multiple DFs accompanied by eruptive BK developed while she was receiving systemic corticosteroid therapy.…”

Multiple Benign Keratoses during Cyclosporin Therapy for Psoriasis

“…There have also been several reports of the development of multiple dysplastic (premalignant) keratoses and squamous cell carcinomas in patients treated with CsA. Ross et al (2) reported multiple eruptive benign keratoses in a patient with psoriasis undergoing CsA therapy.…”

Keratoses Following Topical Steroid for Psoriasis

“…Some tumors, including benign keratoses (1)(2)(3), keratoacanthoma (4,5), and squamous cell carcinoma (6,7), have been reported to occur on psoriatic lesions during or after treatment for psoriasis. This is the first report of the development of multiple benign keratoses on psoriatic lesions following topical steroid treatment.…”