Multiple Exostosis Disease: Study of Three Senegalese Families

Abstract

diffuse masses. The diagnosis of multiple exostosis disease was made in these patients on the basis of epidemiological, clinical, biological, radiological and histological arguments. The information provided by the index cases made it possible to create family trees. Then, a systematic screening for other family cases of multiple exostosis disease was carried out after obtaining consent.Screening was performed on relatives: parents, brothers, sisters or children in the first degree; uncles, aunts or grandparents in the second degree; and first cousins in the third degree. The following data were specified for each patient: epidemiological data (age at the onset and diagnosis of the disease, sex, geographical origin); clinical data (the number of exostosis, their size, their topography, the painful or painless nature); biological data (absence of inflammatory syndrome,

A Rare Case of Hereditary Multiple Exostoses in a Woman

“…This favored location is believed to correlate with exostosis pathogenesis, as they commonly arise in areas of endochondral ossification (ossification involving an intermediate cartilage tissue) found in the metaphysis of long bones and some flat or short bones. In contrast, regions of intramembranous ossification, which bypass the need for an intermediate cartilage stage, such as the skull and clavicle, lack these exostoses ( Moustapha et al, 2019 ).…”